XBI vs. IBBQ ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to Invesco Nasdaq Biotechnology ETF (IBBQ)

XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.46

Average Daily Volume

8,345,258

Number of Holdings ^*

128

* may have additional holdings in another (foreign) market

IBBQ

Invesco Nasdaq Biotechnology ETF

IBBQ Description

The investment seeks to track the investment results (before fees and expenses) of the Nasdaq Biotechnology Index ®. The fund generally will invest at least 90% of its total assets in the securities that comprise the index. Strictly in accordance with its guidelines and mandated procedures, Nasdaq compiles the underlying index, which is a modified market capitalization weighted index that is designed to measure the performance of securities listed on the Nasdaq Stock Market that are classified as either biotechnology or pharmaceutical companies. The index may include securities of large-, mid- and small-capitalization companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$22.34

Average Daily Volume

17,980

Number of Holdings ^*

195

* may have additional holdings in another (foreign) market

Performance

Period	XBI	IBBQ
30 Days	-4.22%	-6.94%
60 Days	-7.47%	-9.48%
90 Days	-6.11%	-8.51%
12 Months	30.77%	17.45%

104 Overlapping Holdings

Symbol	Grade	Weight in XBI	Weight in IBBQ	Overlap
ABUS	D	0.07%	0.07%	0.07%
ACAD	C	0.78%	0.3%	0.3%
ACLX	C	0.79%	0.51%	0.51%
ADMA	B	1.23%	0.48%	0.48%
AGIO	C	0.76%	0.33%	0.33%
AKRO	C	0.43%	0.21%	0.21%
ALEC	F	0.04%	0.04%	0.04%
ALKS	C	1.13%	0.5%	0.5%
ALLO	F	0.11%	0.05%	0.05%
ALNY	D	2.38%	3.26%	2.38%
AMGN	D	2.28%	7.56%	2.28%
ANAB	F	0.12%	0.06%	0.06%
APLS	F	0.86%	0.34%	0.34%
ARCT	F	0.17%	0.05%	0.05%
ARDX	F	0.47%	0.13%	0.13%
ARQT	B	0.42%	0.12%	0.12%
ARWR	D	0.54%	0.25%	0.25%
AVXL	B	0.17%	0.07%	0.07%
BBIO	F	0.87%	0.48%	0.48%
BCRX	D	0.42%	0.16%	0.16%
BEAM	D	0.72%	0.21%	0.21%
BIIB	F	2.19%	2.52%	2.19%
BMRN	F	1.98%	1.3%	1.3%
BPMC	C	1.69%	0.61%	0.61%
CGEM	F	0.25%	0.09%	0.09%
COGT	D	0.16%	0.1%	0.1%
CRNX	B	0.84%	0.47%	0.47%
CRSP	D	1.63%	0.43%	0.43%
CYTK	D	1.79%	0.64%	0.64%
DAWN	D	0.28%	0.14%	0.14%
DNLI	D	0.46%	0.39%	0.39%
DVAX	C	0.49%	0.17%	0.17%
DYN	D	0.78%	0.31%	0.31%
ERAS	C	0.1%	0.08%	0.08%
ETNB	D	0.16%	0.09%	0.09%
EXEL	B	1.23%	1.06%	1.06%
FDMT	F	0.12%	0.05%	0.05%
FOLD	F	0.63%	0.31%	0.31%
GERN	C	0.86%	0.24%	0.24%
GILD	B	2.9%	9.95%	2.9%
HALO	F	1.27%	0.62%	0.62%
HUMA	F	0.18%	0.06%	0.06%
IDYA	F	0.53%	0.24%	0.24%
IMVT	F	0.62%	0.42%	0.42%
INCY	C	3.29%	1.58%	1.58%
INSM	C	2.43%	1.23%	1.23%
IONS	F	1.08%	0.54%	0.54%
IOVA	F	0.88%	0.27%	0.27%
IRON	B	0.34%	0.19%	0.19%
IRWD	F	0.26%	0.07%	0.07%
ITOS	F	0.06%	0.03%	0.03%
JANX	C	0.51%	0.27%	0.27%
KALV	F	0.07%	0.04%	0.04%
KROS	D	0.36%	0.23%	0.23%
KRYS	C	1.29%	0.53%	0.53%
KURA	F	0.24%	0.13%	0.13%
KYMR	D	0.45%	0.29%	0.29%
MDGL	C	2.17%	0.67%	0.67%
MIRM	B	0.57%	0.23%	0.23%
MNKD	B	0.34%	0.2%	0.2%
MRNA	F	1.57%	1.53%	1.53%
MYGN	F	0.27%	0.15%	0.15%
NBIX	C	2.62%	1.28%	1.28%
NRIX	C	0.33%	0.16%	0.16%
NTLA	F	0.58%	0.15%	0.15%
NUVL	D	0.6%	0.56%	0.56%
NVAX	F	0.47%	0.13%	0.13%
OLMA	F	0.13%	0.06%	0.06%
ORIC	F	0.09%	0.06%	0.06%
PCVX	D	0.9%	1.04%	0.9%
PRTA	F	0.13%	0.08%	0.08%
PTCT	B	0.64%	0.32%	0.32%
PTGX	D	0.58%	0.26%	0.26%
RARE	F	0.69%	0.44%	0.44%
RCKT	F	0.28%	0.14%	0.14%
REGN	F	1.8%	5.67%	1.8%
REPL	C	0.18%	0.08%	0.08%
RGNX	D	0.12%	0.05%	0.05%
RLAY	F	0.14%	0.07%	0.07%
RNA	C	1.32%	0.53%	0.53%
ROIV	D	1.18%	0.89%	0.89%
RVMD	B	1.46%	0.99%	0.99%
RXRX	D	0.66%	0.18%	0.18%
RYTM	C	0.61%	0.37%	0.37%
SAGE	F	0.11%	0.03%	0.03%
SANA	F	0.12%	0.06%	0.06%
SMMT	D	0.33%	1.43%	0.33%
SNDX	F	0.44%	0.14%	0.14%
SPRY	C	0.18%	0.15%	0.15%
SRPT	F	2.28%	1.08%	1.08%
SRRK	B	0.49%	0.23%	0.23%
SVRA	F	0.08%	0.05%	0.05%
SWTX	C	0.77%	0.29%	0.29%
TVTX	C	0.26%	0.15%	0.15%
TWST	F	0.93%	0.23%	0.23%
UTHR	C	2.88%	1.75%	1.75%
VCEL	A	0.46%	0.28%	0.28%
VCYT	B	0.53%	0.3%	0.3%
VERA	C	0.57%	0.27%	0.27%
VERV	D	0.15%	0.04%	0.04%
VIR	F	0.2%	0.12%	0.12%
VRTX	D	2.62%	8.34%	2.62%
XNCR	B	0.24%	0.15%	0.15%
YMAB	F	0.06%	0.05%	0.05%

XBI Overweight 24 Positions Relative to IBBQ

Symbol	Grade	Weight
NTRA	A	3.3%
ABBV	F	2.33%
EXAS	D	2.05%
VKTX	F	2.0%
TGTX	B	1.62%
CGON	F	0.42%
CPRX	C	0.41%
CLDX	D	0.34%
VRDN	D	0.3%
CDNA	D	0.24%
APLT	B	0.22%
CDMO	A	0.22%
RCUS	F	0.2%
EBS	C	0.2%
ALT	C	0.18%
ANNX	F	0.16%
STOK	D	0.16%
MDXG	B	0.16%
IMNM	F	0.13%
OCGN	F	0.12%
CELC	F	0.11%
CCCC	F	0.1%
FATE	F	0.08%
SCLX	F	0.06%

XBI Underweight 91 Positions Relative to IBBQ

Symbol	Grade	Weight
AZN	F	-3.97%
ILMN	C	-2.32%
ARGX	A	-1.96%
VTRS	A	-1.65%
SNY	F	-1.51%
RPRX	D	-1.24%
BNTX	D	-1.05%
MEDP	F	-1.04%
ITCI	B	-0.95%
BGNE	D	-0.91%
JAZZ	B	-0.81%
ASND	F	-0.79%
AXSM	B	-0.48%
GH	B	-0.39%
LEGN	D	-0.34%
MRUS	F	-0.34%
XENE	D	-0.33%
EWTX	C	-0.32%
VRNA	A	-0.28%
AMPH	F	-0.23%
LGND	C	-0.22%
SUPN	B	-0.21%
HRMY	F	-0.2%
FTRE	D	-0.19%
NVCR	C	-0.19%
TARS	C	-0.18%
WVE	C	-0.18%
ARVN	F	-0.17%
ZLAB	C	-0.15%
HROW	D	-0.15%
OCUL	C	-0.15%
AUPH	C	-0.13%
INVA	D	-0.13%
ANIP	D	-0.13%
IMCR	C	-0.13%
CNTA	B	-0.12%
ELVN	C	-0.12%
GRFS	C	-0.12%
COLL	F	-0.1%
BCYC	F	-0.09%
GMAB	F	-0.09%
ADPT	C	-0.08%
PLRX	D	-0.08%
EOLS	F	-0.08%
PCRX	C	-0.08%
ABCL	D	-0.08%
CSTL	D	-0.08%
AUTL	F	-0.07%
MRVI	F	-0.07%
HCM	C	-0.06%
GLPG	F	-0.06%
CVAC	F	-0.06%
MLYS	F	-0.06%
PHAT	F	-0.06%
TSHA	C	-0.05%
SIGA	F	-0.05%
XERS	C	-0.05%
PACB	D	-0.05%
TERN	F	-0.05%
RVNC	F	-0.05%
OABI	D	-0.05%
TBPH	B	-0.05%
URGN	F	-0.05%
EYPT	D	-0.05%
PAHC	B	-0.05%
MGTX	C	-0.05%
THRD	D	-0.05%
LXRX	F	-0.04%
PRME	F	-0.04%
PGEN	F	-0.03%
BMEA	F	-0.03%
ZNTL	D	-0.03%
ATAI	B	-0.03%
LYEL	F	-0.03%
VNDA	C	-0.03%
QURE	D	-0.03%
VYGR	F	-0.03%
ACIU	D	-0.03%
ACRS	B	-0.02%
CABA	F	-0.02%
CRBU	D	-0.02%
FULC	F	-0.02%
AMRN	F	-0.02%
EDIT	F	-0.02%
MGNX	D	-0.02%
BLUE	F	-0.01%
ALXO	F	-0.01%
OVID	D	-0.01%
CHRS	D	-0.01%
VTYX	F	-0.01%
RAPT	F	-0.0%