SBIO vs. AVSD ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Avantis Responsible International Equity ETF (AVSD)

SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$37.54

Average Daily Volume

5,439

Number of Holdings ^*

* may have additional holdings in another (foreign) market

AVSD

Avantis Responsible International Equity ETF

AVSD Description

Avantis Responsible International Equity ETF is an exchange traded fund launched and managed by American Century Investment Management Inc. The fund invests in public equity markets of global ex-US region. The fund invests in stocks of companies operating across diversified sectors. It invests in value stocks of small-cap companies. It invests in stocks of companies that are deemed socially conscious in their business dealings and directly promote environmental responsibility. The fund does not invest in stocks of companies operating across oil and gas production or distribution; manufacture or sale of civilian firearms and ammunition; manufacture of chemical, biological, or nuclear weapons and related systems or components; factory farming; palm oil production; production or sale of tobacco or cannabis; gambling; or adult entertainment, carbon emissions intensity and thermal coal sectors. The fund employs proprietary research to create its portfolio. Avantis Responsible International Equity ETF is domiciled in the United States.

Grade (RS Rating)

Last Trade

$59.89

Average Daily Volume

3,679

Number of Holdings ^*

* may have additional holdings in another (foreign) market

Performance

Period	SBIO	AVSD
30 Days	0.34%	0.38%
60 Days	5.63%	8.63%
90 Days	14.55%	6.13%
12 Months	43.65%	29.61%

1 Overlapping Holdings

	Symbol	Grade	Weight in SBIO	Weight in AVSD	Overlap
	GLPG	D	1.29%	0.02%	0.02%

SBIO Overweight 82 Positions Relative to AVSD

Symbol	Grade	Weight
KRYS	D	3.49%
RNA	B	3.28%
CORT	B	3.08%
ALKS	B	3.06%
ACLX	C	2.99%
IMVT	F	2.79%
DNLI	C	2.75%
CRNX	C	2.72%
MRUS	D	2.25%
FOLD	F	2.14%
XENE	D	1.94%
PTCT	C	1.92%
GERN	D	1.83%
CGON	C	1.8%
ACAD	F	1.76%
IDYA	F	1.76%
PTGX	C	1.74%
AGIO	D	1.73%
VERA	C	1.69%
VRNA	C	1.59%
EWTX	B	1.58%
ZLAB	B	1.55%
CLDX	F	1.48%
NTLA	F	1.41%
VCEL	F	1.41%
KROS	B	1.39%
AKRO	C	1.32%
MIRM	D	1.27%
ARVN	F	1.16%
MNKD	C	1.14%
SNDX	F	1.11%
IMCR	F	1.06%
BCRX	D	1.06%
KURA	F	1.01%
IRON	C	1.01%
VRDN	A	0.96%
RCUS	F	0.93%
SPRY	B	0.89%
XNCR	D	0.86%
DAWN	D	0.86%
TARS	C	0.84%
COGT	C	0.84%
LBPH	D	0.75%
PRTA	F	0.74%
AUPH	C	0.7%
PHVS	D	0.69%
APLT	B	0.68%
ANAB	D	0.6%
LQDA	F	0.54%
ETNB	F	0.52%
ERAS	D	0.51%
REPL	B	0.51%
OLMA	F	0.49%
SVRA	F	0.48%
PLRX	F	0.48%
ALLO	F	0.45%
FLGT	F	0.43%
IRWD	F	0.42%
ARCT	D	0.42%
FULC	F	0.41%
MLYS	B	0.4%
ANNX	B	0.4%
URGN	F	0.39%
YMAB	B	0.39%
FDMT	F	0.38%
CELC	F	0.38%
ALEC	F	0.33%
AVXL	D	0.32%
ALT	F	0.31%
CMPS	F	0.31%
AURA	C	0.28%
TBPH	F	0.27%
ACIU	D	0.25%
ITOS	F	0.24%
GHRS	F	0.23%
ALDX	C	0.22%
STRO	F	0.2%
INZY	D	0.2%
ZNTL	F	0.19%
VNDA	F	0.18%
ENTA	F	0.14%
HLVX	F	0.06%

SBIO Underweight 81 Positions Relative to AVSD

Symbol	Grade	Weight
NVO	F	-1.43%
NVS	D	-0.89%
ASML	F	-0.85%
HSBC	B	-0.84%
AZN	D	-0.66%
TM	D	-0.51%
GSK	F	-0.44%
ING	D	-0.43%
BCS	C	-0.43%
SAP	C	-0.4%
LYG	C	-0.4%
TD	C	-0.38%
UL	C	-0.36%
BBVA	D	-0.36%
SNY	C	-0.36%
MUFG	D	-0.35%
DEO	B	-0.34%
SMFG	D	-0.32%
STM	F	-0.3%
ORAN	D	-0.29%
RELX	C	-0.29%
SAN	C	-0.29%
HMC	D	-0.29%
AER	D	-0.21%
NWG	D	-0.21%
MFG	D	-0.2%
CNI	D	-0.18%
PHG	A	-0.18%
VOD	C	-0.17%
ABBV	A	-0.16%
ERIC	B	-0.16%
BUD	A	-0.14%
STLA	F	-0.14%
TEF	C	-0.13%
SW	C	-0.13%
HLN	C	-0.12%
LOGI	D	-0.1%
WFG	A	-0.09%
CHKP	C	-0.08%
TAK	D	-0.08%
SE	B	-0.08%
SNN	D	-0.08%
TEVA	D	-0.07%
XRX	D	-0.07%
GLNG	A	-0.07%
OTEX	D	-0.07%
ARGX	A	-0.06%
TEAM	D	-0.06%
GMAB	F	-0.05%
NOK	B	-0.05%
ZIM	B	-0.05%
SPOT	B	-0.05%
PSO	D	-0.05%
FMS	B	-0.04%
CSTM	F	-0.04%
RBA	D	-0.04%
CCEP	C	-0.04%
QGEN	D	-0.03%
WPP	C	-0.03%
DOOO	F	-0.03%
GLBE	C	-0.02%
WIX	D	-0.02%
ICLR	F	-0.02%
NICE	F	-0.02%
AEI	B	-0.02%
PIXY	F	-0.01%
MBAVU	C	-0.01%
MNTX	D	-0.01%
NNDM	D	-0.01%
LSPD	B	-0.01%
SPNS	C	-0.01%
GRAB	B	-0.01%
CYBR	C	-0.01%
DBVT	F	-0.0%
NAK	D	-0.0%
FUTU	B	-0.0%
VGR	B	-0.0%
CRNT	F	-0.0%
MGIC	C	-0.0%
ITRN	D	-0.0%
SSBI	F	-0.0%

SBIO: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Specialty & Generic Medical Care Facilities