IBBQ vs. BBC ETF Comparison

Comparison of Invesco Nasdaq Biotechnology ETF (IBBQ) to Virtus LifeSci Biotech Clinical Trials ETF (BBC)

IBBQ

Invesco Nasdaq Biotechnology ETF

IBBQ Description

The investment seeks to track the investment results (before fees and expenses) of the Nasdaq Biotechnology Index ®. The fund generally will invest at least 90% of its total assets in the securities that comprise the index. Strictly in accordance with its guidelines and mandated procedures, Nasdaq compiles the underlying index, which is a modified market capitalization weighted index that is designed to measure the performance of securities listed on the Nasdaq Stock Market that are classified as either biotechnology or pharmaceutical companies. The index may include securities of large-, mid- and small-capitalization companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$22.50

Average Daily Volume

17,582

Number of Holdings ^*

195

* may have additional holdings in another (foreign) market

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$26.12

Average Daily Volume

1,806

Number of Holdings ^*

101

* may have additional holdings in another (foreign) market

Performance

Period	IBBQ	BBC
30 Days	-6.27%	-12.22%
60 Days	-8.87%	-10.51%
90 Days	-8.76%	-5.99%
12 Months	17.68%	38.68%

76 Overlapping Holdings

Symbol	Grade	Weight in IBBQ	Weight in BBC	Overlap
ABCL	D	0.08%	0.69%	0.08%
ABUS	D	0.07%	1.0%	0.07%
ACLX	C	0.51%	1.36%	0.51%
AKRO	B	0.21%	0.99%	0.21%
ALEC	F	0.04%	0.71%	0.04%
ALLO	F	0.05%	0.77%	0.05%
ALXO	F	0.01%	0.13%	0.01%
ANAB	F	0.06%	0.68%	0.06%
ARCT	F	0.05%	0.44%	0.05%
ARQT	B	0.12%	0.86%	0.12%
ARVN	F	0.17%	0.74%	0.17%
ARWR	D	0.25%	0.61%	0.25%
AUTL	F	0.07%	0.59%	0.07%
BCYC	F	0.09%	0.78%	0.09%
BEAM	D	0.21%	0.83%	0.21%
CABA	F	0.02%	0.21%	0.02%
CGEM	F	0.09%	0.55%	0.09%
CNTA	B	0.12%	1.4%	0.12%
COGT	D	0.1%	0.86%	0.1%
CRNX	C	0.47%	1.01%	0.47%
CVAC	F	0.06%	0.55%	0.06%
CYTK	F	0.64%	0.82%	0.64%
DNLI	D	0.39%	0.98%	0.39%
DYN	F	0.31%	0.73%	0.31%
EDIT	F	0.02%	0.42%	0.02%
ELVN	D	0.12%	0.96%	0.12%
ERAS	C	0.08%	1.06%	0.08%
ETNB	C	0.09%	0.74%	0.09%
EWTX	C	0.32%	1.52%	0.32%
FDMT	F	0.05%	0.31%	0.05%
FULC	F	0.02%	0.33%	0.02%
IDYA	F	0.24%	0.59%	0.24%
IMVT	F	0.42%	0.87%	0.42%
IRON	B	0.19%	1.32%	0.19%
ITOS	F	0.03%	0.44%	0.03%
JANX	C	0.27%	1.0%	0.27%
KROS	D	0.23%	0.99%	0.23%
KURA	F	0.13%	0.64%	0.13%
KYMR	D	0.29%	1.04%	0.29%
LYEL	F	0.03%	0.37%	0.03%
MGNX	F	0.02%	0.66%	0.02%
MLYS	F	0.06%	0.78%	0.06%
MRUS	F	0.34%	0.7%	0.34%
NRIX	C	0.16%	1.19%	0.16%
NTLA	F	0.15%	0.47%	0.15%
NUVL	C	0.56%	0.95%	0.56%
OLMA	F	0.06%	0.64%	0.06%
ORIC	F	0.06%	0.96%	0.06%
PCVX	D	1.04%	1.02%	1.02%
PGEN	F	0.03%	0.42%	0.03%
PLRX	D	0.08%	0.9%	0.08%
PRME	F	0.04%	0.37%	0.04%
PRTA	F	0.08%	0.57%	0.08%
PTGX	D	0.26%	1.04%	0.26%
QURE	C	0.03%	1.02%	0.03%
RCKT	F	0.14%	0.53%	0.14%
REPL	D	0.08%	0.99%	0.08%
RGNX	D	0.05%	0.64%	0.05%
RLAY	F	0.07%	0.57%	0.07%
RNA	C	0.53%	0.91%	0.53%
RVMD	C	0.99%	1.2%	0.99%
RXRX	F	0.18%	0.57%	0.18%
SANA	F	0.06%	0.29%	0.06%
SMMT	D	1.43%	1.96%	1.43%
SNDX	F	0.14%	0.66%	0.14%
SRRK	C	0.23%	2.43%	0.23%
SVRA	F	0.05%	0.64%	0.05%
TERN	F	0.05%	0.67%	0.05%
TSHA	C	0.05%	0.43%	0.05%
VERA	C	0.27%	1.07%	0.27%
VERV	F	0.04%	0.74%	0.04%
VIR	D	0.12%	0.67%	0.12%
WVE	C	0.18%	1.83%	0.18%
XENE	D	0.33%	0.91%	0.33%
XNCR	B	0.15%	0.94%	0.15%
ZNTL	F	0.03%	0.32%	0.03%

IBBQ Overweight 119 Positions Relative to BBC

Symbol	Grade	Weight
GILD	C	9.95%
VRTX	D	8.34%
AMGN	F	7.56%
REGN	F	5.67%
AZN	F	3.97%
ALNY	D	3.26%
BIIB	F	2.52%
ILMN	C	2.32%
ARGX	B	1.96%
UTHR	C	1.75%
VTRS	A	1.65%
INCY	C	1.58%
MRNA	F	1.53%
SNY	F	1.51%
BMRN	F	1.3%
NBIX	C	1.28%
RPRX	D	1.24%
INSM	C	1.23%
SRPT	F	1.08%
EXEL	B	1.06%
BNTX	C	1.05%
MEDP	D	1.04%
ITCI	C	0.95%
BGNE	D	0.91%
ROIV	C	0.89%
JAZZ	B	0.81%
ASND	F	0.79%
MDGL	B	0.67%
HALO	F	0.62%
BPMC	B	0.61%
IONS	F	0.54%
KRYS	C	0.53%
ALKS	C	0.5%
ADMA	B	0.48%
AXSM	B	0.48%
BBIO	F	0.48%
RARE	F	0.44%
CRSP	D	0.43%
GH	B	0.39%
RYTM	C	0.37%
LEGN	D	0.34%
APLS	F	0.34%
AGIO	C	0.33%
PTCT	B	0.32%
FOLD	F	0.31%
VCYT	B	0.3%
ACAD	C	0.3%
SWTX	C	0.29%
VRNA	B	0.28%
VCEL	B	0.28%
IOVA	F	0.27%
GERN	D	0.24%
MIRM	B	0.23%
TWST	F	0.23%
AMPH	F	0.23%
LGND	C	0.22%
SUPN	C	0.21%
MNKD	C	0.2%
HRMY	D	0.2%
FTRE	D	0.19%
NVCR	C	0.19%
TARS	C	0.18%
DVAX	C	0.17%
BCRX	D	0.16%
ZLAB	C	0.15%
TVTX	C	0.15%
SPRY	C	0.15%
HROW	D	0.15%
MYGN	F	0.15%
OCUL	D	0.15%
DAWN	D	0.14%
AUPH	B	0.13%
ARDX	F	0.13%
NVAX	F	0.13%
INVA	D	0.13%
ANIP	F	0.13%
IMCR	D	0.13%
GRFS	C	0.12%
COLL	F	0.1%
GMAB	F	0.09%
ADPT	C	0.08%
EOLS	D	0.08%
PCRX	C	0.08%
CSTL	D	0.08%
MRVI	F	0.07%
AVXL	B	0.07%
IRWD	F	0.07%
HCM	D	0.06%
GLPG	F	0.06%
HUMA	F	0.06%
PHAT	F	0.06%
SIGA	F	0.05%
XERS	C	0.05%
PACB	F	0.05%
RVNC	F	0.05%
OABI	F	0.05%
TBPH	B	0.05%
URGN	F	0.05%
EYPT	D	0.05%
YMAB	F	0.05%
PAHC	C	0.05%
MGTX	C	0.05%
THRD	F	0.05%
LXRX	F	0.04%
KALV	F	0.04%
BMEA	F	0.03%
ATAI	C	0.03%
VNDA	C	0.03%
VYGR	F	0.03%
SAGE	F	0.03%
ACIU	D	0.03%
ACRS	B	0.02%
CRBU	D	0.02%
AMRN	F	0.02%
BLUE	F	0.01%
OVID	F	0.01%
CHRS	D	0.01%
VTYX	F	0.01%
RAPT	F	0.0%

IBBQ Underweight 25 Positions Relative to BBC

Symbol	Grade	Weight
LBPH	A	-2.59%
APLT	C	-1.43%
BLTE	B	-1.43%
VRDN	D	-1.33%
SAVA	C	-1.17%
IGMS	F	-1.03%
PHVS	C	-0.97%
ANNX	F	-0.88%
VKTX	F	-0.83%
CGON	F	-0.82%
RCUS	F	-0.8%
NUVB	C	-0.76%
CELC	F	-0.71%
TYRA	F	-0.67%
CMPS	F	-0.63%
LQDA	F	-0.63%
LRMR	D	-0.6%
STOK	F	-0.59%
SLN	F	-0.56%
CLDX	F	-0.56%
IMTX	F	-0.55%
IMNM	F	-0.53%
HLVX	F	-0.11%
AVTE	D	-0.09%
SCLX	F	-0.09%