BBC vs. BIB ETF Comparison

Comparison of Virtus LifeSci Biotech Clinical Trials ETF (BBC) to ProShares Ultra Nasdaq Biotechnology (BIB)

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$25.96

Average Daily Volume

1,790

Number of Holdings ^*

101

* may have additional holdings in another (foreign) market

BIB

ProShares Ultra Nasdaq Biotechnology

BIB Description

The investment seeks daily investment results that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology Index®. The fund invests in securities and derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times (2x) the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$55.30

Average Daily Volume

13,845

Number of Holdings ^*

195

* may have additional holdings in another (foreign) market

Performance

Period	BBC	BIB
30 Days	-12.44%	-14.23%
60 Days	-10.35%	-18.82%
90 Days	-3.70%	-17.45%
12 Months	39.98%	26.68%

76 Overlapping Holdings

Symbol	Grade	Weight in BBC	Weight in BIB	Overlap
ABCL	D	0.69%	0.06%	0.06%
ABUS	D	1.0%	0.05%	0.05%
ACLX	C	1.36%	0.39%	0.39%
AKRO	C	0.99%	0.17%	0.17%
ALEC	F	0.71%	0.03%	0.03%
ALLO	F	0.77%	0.04%	0.04%
ALXO	F	0.13%	0.01%	0.01%
ANAB	F	0.68%	0.05%	0.05%
ARCT	F	0.44%	0.04%	0.04%
ARQT	B	0.86%	0.09%	0.09%
ARVN	F	0.74%	0.13%	0.13%
ARWR	D	0.61%	0.19%	0.19%
AUTL	F	0.59%	0.05%	0.05%
BCYC	F	0.78%	0.06%	0.06%
BEAM	D	0.83%	0.16%	0.16%
CABA	F	0.21%	0.01%	0.01%
CGEM	F	0.55%	0.06%	0.06%
CNTA	B	1.4%	0.09%	0.09%
COGT	D	0.86%	0.08%	0.08%
CRNX	B	1.01%	0.35%	0.35%
CVAC	F	0.55%	0.05%	0.05%
CYTK	D	0.82%	0.5%	0.5%
DNLI	D	0.98%	0.28%	0.28%
DYN	D	0.73%	0.24%	0.24%
EDIT	F	0.42%	0.02%	0.02%
ELVN	C	0.96%	0.1%	0.1%
ERAS	C	1.06%	0.06%	0.06%
ETNB	D	0.74%	0.07%	0.07%
EWTX	C	1.52%	0.24%	0.24%
FDMT	F	0.31%	0.04%	0.04%
FULC	F	0.33%	0.02%	0.02%
IDYA	F	0.59%	0.18%	0.18%
IMVT	F	0.87%	0.3%	0.3%
IRON	B	1.32%	0.14%	0.14%
ITOS	F	0.44%	0.02%	0.02%
JANX	C	1.0%	0.2%	0.2%
KROS	D	0.99%	0.17%	0.17%
KURA	F	0.64%	0.1%	0.1%
KYMR	D	1.04%	0.22%	0.22%
LYEL	F	0.37%	0.02%	0.02%
MGNX	D	0.66%	0.02%	0.02%
MLYS	F	0.78%	0.05%	0.05%
MRUS	F	0.7%	0.25%	0.25%
NRIX	C	1.19%	0.11%	0.11%
NTLA	F	0.47%	0.12%	0.12%
NUVL	D	0.95%	0.42%	0.42%
OLMA	F	0.64%	0.04%	0.04%
ORIC	F	0.96%	0.05%	0.05%
PCVX	D	1.02%	0.79%	0.79%
PGEN	F	0.42%	0.02%	0.02%
PLRX	D	0.9%	0.06%	0.06%
PRME	F	0.37%	0.03%	0.03%
PRTA	F	0.57%	0.06%	0.06%
PTGX	D	1.04%	0.19%	0.19%
QURE	D	1.02%	0.02%	0.02%
RCKT	F	0.53%	0.1%	0.1%
REPL	C	0.99%	0.06%	0.06%
RGNX	D	0.64%	0.04%	0.04%
RLAY	F	0.57%	0.05%	0.05%
RNA	C	0.91%	0.39%	0.39%
RVMD	B	1.2%	0.74%	0.74%
RXRX	D	0.57%	0.14%	0.14%
SANA	F	0.29%	0.04%	0.04%
SMMT	D	1.96%	1.12%	1.12%
SNDX	F	0.66%	0.11%	0.11%
SRRK	B	2.43%	0.17%	0.17%
SVRA	F	0.64%	0.04%	0.04%
TERN	F	0.67%	0.03%	0.03%
TSHA	C	0.43%	0.04%	0.04%
VERA	C	1.07%	0.2%	0.2%
VERV	D	0.74%	0.03%	0.03%
VIR	F	0.67%	0.08%	0.08%
WVE	C	1.83%	0.13%	0.13%
XENE	D	0.91%	0.24%	0.24%
XNCR	B	0.94%	0.12%	0.12%
ZNTL	D	0.32%	0.02%	0.02%

BBC Overweight 25 Positions Relative to BIB

Symbol	Grade	Weight
LBPH	A	2.59%
APLT	B	1.43%
BLTE	B	1.43%
VRDN	D	1.33%
SAVA	D	1.17%
IGMS	F	1.03%
PHVS	D	0.97%
ANNX	F	0.88%
VKTX	F	0.83%
CGON	F	0.82%
RCUS	F	0.8%
NUVB	C	0.76%
CELC	F	0.71%
TYRA	F	0.67%
CMPS	F	0.63%
LQDA	F	0.63%
LRMR	D	0.6%
STOK	D	0.59%
SLN	F	0.56%
CLDX	D	0.56%
IMTX	F	0.55%
IMNM	F	0.53%
HLVX	F	0.11%
AVTE	C	0.09%
SCLX	F	0.09%

BBC Underweight 119 Positions Relative to BIB

Symbol	Grade	Weight
GILD	B	-7.52%
VRTX	D	-6.33%
AMGN	D	-5.61%
REGN	F	-4.32%
AZN	F	-3.01%
ALNY	D	-2.43%
BIIB	F	-1.87%
ILMN	C	-1.7%
ARGX	A	-1.49%
UTHR	C	-1.3%
VTRS	A	-1.26%
MRNA	F	-1.24%
INCY	C	-1.21%
SNY	F	-1.16%
NBIX	C	-0.97%
BMRN	F	-0.96%
RPRX	D	-0.94%
INSM	C	-0.93%
SRPT	F	-0.81%
BNTX	D	-0.81%
EXEL	B	-0.8%
MEDP	F	-0.78%
ITCI	B	-0.71%
BGNE	D	-0.68%
ROIV	D	-0.67%
JAZZ	B	-0.59%
ASND	F	-0.58%
MDGL	C	-0.54%
BPMC	C	-0.47%
HALO	F	-0.44%
KRYS	C	-0.41%
IONS	F	-0.4%
ALKS	C	-0.37%
ADMA	B	-0.37%
AXSM	B	-0.36%
BBIO	F	-0.34%
CRSP	D	-0.33%
RARE	F	-0.33%
GH	B	-0.29%
RYTM	C	-0.29%
APLS	F	-0.26%
AGIO	C	-0.25%
PTCT	B	-0.25%
LEGN	D	-0.25%
VCYT	B	-0.23%
ACAD	C	-0.23%
FOLD	F	-0.23%
VRNA	A	-0.21%
IOVA	F	-0.21%
SWTX	C	-0.21%
VCEL	A	-0.21%
TWST	F	-0.2%
GERN	C	-0.19%
AMPH	F	-0.18%
LGND	C	-0.17%
SUPN	B	-0.16%
MIRM	B	-0.16%
MNKD	B	-0.15%
HRMY	F	-0.15%
FTRE	D	-0.14%
TARS	C	-0.14%
NVCR	C	-0.14%
BCRX	D	-0.12%
DVAX	C	-0.12%
DAWN	D	-0.11%
TVTX	C	-0.11%
SPRY	C	-0.11%
HROW	D	-0.11%
OCUL	C	-0.11%
MYGN	F	-0.11%
ARDX	F	-0.1%
INVA	D	-0.1%
IMCR	C	-0.1%
ZLAB	C	-0.1%
NVAX	F	-0.1%
GRFS	C	-0.09%
AUPH	C	-0.09%
ANIP	D	-0.09%
COLL	F	-0.08%
GMAB	F	-0.07%
ADPT	C	-0.06%
EOLS	F	-0.06%
PCRX	C	-0.06%
CSTL	D	-0.06%
PHAT	F	-0.05%
AVXL	B	-0.05%
IRWD	F	-0.05%
MRVI	F	-0.05%
XERS	C	-0.04%
OABI	D	-0.04%
SIGA	F	-0.04%
TBPH	B	-0.04%
URGN	F	-0.04%
MGTX	C	-0.04%
EYPT	D	-0.04%
THRD	D	-0.04%
YMAB	F	-0.04%
PAHC	B	-0.04%
HCM	C	-0.04%
HUMA	F	-0.04%
GLPG	F	-0.04%
ACIU	D	-0.03%
LXRX	F	-0.03%
KALV	F	-0.03%
RVNC	F	-0.03%
PACB	D	-0.03%
AMRN	F	-0.02%
ACRS	B	-0.02%
BMEA	F	-0.02%
ATAI	B	-0.02%
VNDA	C	-0.02%
SAGE	F	-0.02%
VYGR	F	-0.02%
BLUE	F	-0.01%
OVID	D	-0.01%
CHRS	D	-0.01%
VTYX	F	-0.01%
CRBU	D	-0.01%
RAPT	F	-0.0%