Genome Editing Stocks List
Symbol | Grade | Name | % Change | |
---|---|---|---|---|
EDIT | F | Editas Medicine, Inc. | 2.64 | |
DTIL | F | Precision BioSciences, Inc. | -1.38 | |
NTLA | F | Intellia Therapeutics, Inc. | 3.61 | |
CRSP | F | CRISPR Therapeutics AG | 1.48 | |
MGX | F | Metagenomi, Inc. | -7.57 | |
ABEO | C | Abeona Therapeutics Inc. | 5.58 |
Related Industries: Biotechnology
Symbol | Grade | Name | Weight | |
---|---|---|---|---|
ARKG | F | ARK Genomic Revolution Multi-Sector ETF | 12.16 | |
ARKK | C | ARK Innovation ETF | 8.7 | |
GNOM | D | Global X Genomics & Biotechnology ETF | 8.57 | |
MOON | D | Direxion Moonshot Innovators ETF | 4.99 | |
NXTE | B | AXS Green Alpha ETF | 3.86 |
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- Genome Editing
Genome editing, or genome engineering, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site specific locations.
In 2018, the common methods for such editing use engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations ('edits').
As of 2015 four families of engineered nucleases were used: meganucleases, zinc finger nucleases (ZFNs), transcription activator-like effector-based nucleases (TALEN), and the clustered regularly interspaced short palindromic repeats (CRISPR/Cas9) system. Nine genome editors were available as of 2017.Genome editing with engineered nucleases, i.e. all three major classes of these enzymes—zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and engineered meganucleases—were selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science as 2015 Breakthrough of the Year.
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