XBI vs. PBE ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to PowerShares Dynamic Biotech & Genome (PBE)
XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$94.46

Average Daily Volume

8,345,258

Number of Holdings *

128

* may have additional holdings in another (foreign) market
PBE

PowerShares Dynamic Biotech & Genome

PBE Description The PowerShares Dynamic Biotechnology & Genome Portfolio (Fund) is based on the Dynamic Biotech & Genome IntellidexSM Index (Intellidex Index). The Fund will normally invest at least 90% of its total assets in common stocks that comprise the Index. The Intellidex Index is designed to provide capital appreciation by thoroughly evaluating companies based on a variety of investment merit criteria, including price momentum, earnings momentum, quality, management action, and value. The Underlying Intellidex Index is comprised of common stocks of 30 US biotechnology and genome companies. These are companies that are principally engaged in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes and companies that benefit significantly from scientific and technological advances biotechnology and genetic engineering and reseach. The Fund and the Index are rebalanced and reconstituted quarterly in February, May, August and November.

Grade (RS Rating)

Last Trade

$68.40

Average Daily Volume

6,342

Number of Holdings *

30

* may have additional holdings in another (foreign) market
Performance
Period XBI PBE
30 Days -4.22% -0.98%
60 Days -7.47% -5.20%
90 Days -6.11% -4.17%
12 Months 30.77% 20.11%
24 Overlapping Holdings
Symbol Grade Weight in XBI Weight in PBE Overlap
ACAD C 0.78% 3.06% 0.78%
ALNY D 2.38% 4.78% 2.38%
AMGN D 2.28% 4.7% 2.28%
BCRX D 0.42% 2.56% 0.42%
BIIB F 2.19% 4.21% 2.19%
BMRN F 1.98% 3.76% 1.98%
BPMC C 1.69% 2.91% 1.69%
CDNA D 0.24% 1.92% 0.24%
CPRX C 0.41% 3.0% 0.41%
EXEL B 1.23% 3.86% 1.23%
HALO F 1.27% 2.42% 1.27%
INCY C 3.29% 3.35% 3.29%
MNKD B 0.34% 3.7% 0.34%
MYGN F 0.27% 1.61% 0.27%
NBIX C 2.62% 4.18% 2.62%
NTRA A 3.3% 3.56% 3.3%
NVAX F 0.47% 1.83% 0.47%
PTGX D 0.58% 2.75% 0.58%
REGN F 1.8% 3.38% 1.8%
TGTX B 1.62% 3.78% 1.62%
UTHR C 2.88% 5.74% 2.88%
VCEL A 0.46% 2.79% 0.46%
VCYT B 0.53% 3.28% 0.53%
XNCR B 0.24% 3.88% 0.24%
XBI Overweight 104 Positions Relative to PBE
Symbol Grade Weight
GILD B 2.9%
VRTX D 2.62%
INSM C 2.43%
ABBV F 2.33%
SRPT F 2.28%
MDGL C 2.17%
EXAS D 2.05%
VKTX F 2.0%
CYTK D 1.79%
CRSP D 1.63%
MRNA F 1.57%
RVMD B 1.46%
RNA C 1.32%
KRYS C 1.29%
ADMA B 1.23%
ROIV D 1.18%
ALKS C 1.13%
IONS F 1.08%
TWST F 0.93%
PCVX D 0.9%
IOVA F 0.88%
BBIO F 0.87%
APLS F 0.86%
GERN C 0.86%
CRNX B 0.84%
ACLX C 0.79%
DYN D 0.78%
SWTX C 0.77%
AGIO C 0.76%
BEAM D 0.72%
RARE F 0.69%
RXRX D 0.66%
PTCT B 0.64%
FOLD F 0.63%
IMVT F 0.62%
RYTM C 0.61%
NUVL D 0.6%
NTLA F 0.58%
VERA C 0.57%
MIRM B 0.57%
ARWR D 0.54%
IDYA F 0.53%
JANX C 0.51%
SRRK B 0.49%
DVAX C 0.49%
ARDX F 0.47%
DNLI D 0.46%
KYMR D 0.45%
SNDX F 0.44%
AKRO C 0.43%
CGON F 0.42%
ARQT B 0.42%
KROS D 0.36%
IRON B 0.34%
CLDX D 0.34%
NRIX C 0.33%
SMMT D 0.33%
VRDN D 0.3%
RCKT F 0.28%
DAWN D 0.28%
IRWD F 0.26%
TVTX C 0.26%
CGEM F 0.25%
KURA F 0.24%
APLT B 0.22%
CDMO A 0.22%
RCUS F 0.2%
VIR F 0.2%
EBS C 0.2%
REPL C 0.18%
HUMA F 0.18%
ALT C 0.18%
SPRY C 0.18%
AVXL B 0.17%
ARCT F 0.17%
ANNX F 0.16%
STOK D 0.16%
ETNB D 0.16%
MDXG B 0.16%
COGT D 0.16%
VERV D 0.15%
RLAY F 0.14%
OLMA F 0.13%
IMNM F 0.13%
PRTA F 0.13%
OCGN F 0.12%
ANAB F 0.12%
FDMT F 0.12%
SANA F 0.12%
RGNX D 0.12%
ALLO F 0.11%
CELC F 0.11%
SAGE F 0.11%
CCCC F 0.1%
ERAS C 0.1%
ORIC F 0.09%
FATE F 0.08%
SVRA F 0.08%
ABUS D 0.07%
KALV F 0.07%
SCLX F 0.06%
YMAB F 0.06%
ITOS F 0.06%
ALEC F 0.04%
XBI Underweight 6 Positions Relative to PBE
Symbol Grade Weight
ILMN C -5.64%
TECH F -2.89%
OPK B -2.78%
RGEN D -2.76%
QGEN D -2.59%
COLL F -2.27%
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