SBIO vs. IBB ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to iShares Nasdaq Biotechnology Index Fund (IBB)

SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$37.20

Average Daily Volume

8,661

Number of Holdings ^*

* may have additional holdings in another (foreign) market

IBB

iShares Nasdaq Biotechnology Index Fund

IBB Description

The investment seeks to track the investment results of an index composed of biotechnology and pharmaceutical equities listed on the NASDAQ. The fund generally invests at least 90% of its assets in securities of the underlying index and in depositary receipts representing securities of the underlying index. The underlying index contains securities of NASDAQÂ® listed companies that are classified according to the Industry Classification Benchmark as either biotechnology or pharmaceuticals and that also meet other eligibility criteria determined by The NASDAQ OMX Group, Inc. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$136.10

Average Daily Volume

1,176,846

Number of Holdings ^*

184

* may have additional holdings in another (foreign) market

Performance

Period	SBIO	IBB
30 Days	-5.42%	-5.49%
60 Days	-4.09%	-8.03%
90 Days	0.49%	-8.01%
12 Months	48.12%	14.75%

59 Overlapping Holdings

Symbol	Grade	Weight in SBIO	Weight in IBB	Overlap
ACAD	C	1.89%	0.28%	0.28%
ACLX	C	3.19%	0.37%	0.37%
AGIO	C	2.05%	0.32%	0.32%
AKRO	B	1.32%	0.19%	0.19%
ALEC	F	0.28%	0.03%	0.03%
ALKS	C	3.15%	0.47%	0.47%
ALLO	F	0.35%	0.03%	0.03%
ANAB	F	0.36%	0.05%	0.05%
ARCT	F	0.31%	0.05%	0.05%
ARVN	F	1.06%	0.14%	0.14%
AUPH	B	0.78%	0.11%	0.11%
AVXL	B	0.42%	0.07%	0.07%
BCRX	D	0.99%	0.15%	0.15%
COGT	D	0.69%	0.08%	0.08%
CRNX	C	2.95%	0.49%	0.49%
DAWN	D	0.82%	0.08%	0.08%
DNLI	D	2.36%	0.3%	0.3%
ERAS	C	0.51%	0.05%	0.05%
ETNB	C	0.57%	0.08%	0.08%
EWTX	C	1.92%	0.19%	0.19%
FDMT	F	0.31%	0.04%	0.04%
FLGT	F	0.35%	0.04%	0.04%
FOLD	F	1.95%	0.29%	0.29%
FULC	F	0.33%	0.02%	0.02%
GERN	D	1.48%	0.22%	0.22%
IDYA	F	1.53%	0.21%	0.21%
IMVT	F	2.66%	0.16%	0.16%
IRON	B	1.21%	0.1%	0.1%
IRWD	F	0.44%	0.06%	0.06%
ITOS	F	0.19%	0.02%	0.02%
KROS	D	1.4%	0.17%	0.17%
KRYS	C	3.39%	0.45%	0.45%
KURA	F	0.83%	0.11%	0.11%
MIRM	B	1.47%	0.17%	0.17%
MLYS	F	0.39%	0.03%	0.03%
MNKD	C	1.26%	0.19%	0.19%
MRUS	F	2.21%	0.27%	0.27%
NTLA	F	0.94%	0.15%	0.15%
OLMA	F	0.37%	0.05%	0.05%
PLRX	D	0.53%	0.07%	0.07%
PRTA	F	0.52%	0.07%	0.07%
PTCT	B	2.02%	0.31%	0.31%
PTGX	D	1.61%	0.23%	0.23%
RCUS	F	0.95%	0.07%	0.07%
REPL	D	0.5%	0.06%	0.06%
RNA	C	3.29%	0.5%	0.5%
SNDX	F	0.93%	0.13%	0.13%
SPRY	C	0.88%	0.07%	0.07%
SVRA	F	0.34%	0.03%	0.03%
TARS	C	1.16%	0.16%	0.16%
TBPH	B	0.32%	0.05%	0.05%
URGN	F	0.34%	0.04%	0.04%
VCEL	B	1.73%	0.28%	0.28%
VERA	C	1.82%	0.2%	0.2%
VNDA	C	0.2%	0.03%	0.03%
XENE	D	2.01%	0.3%	0.3%
XNCR	B	0.98%	0.17%	0.17%
YMAB	F	0.34%	0.04%	0.04%
ZNTL	F	0.17%	0.02%	0.02%

SBIO Overweight 24 Positions Relative to IBB

Symbol	Grade	Weight
CORT	B	3.66%
VRNA	B	1.98%
ZLAB	C	1.79%
CGON	F	1.57%
LBPH	A	1.4%
GLPG	F	1.19%
IMCR	D	1.07%
CLDX	F	1.06%
VRDN	D	0.84%
PHVS	C	0.76%
APLT	C	0.72%
LQDA	F	0.54%
ANNX	F	0.4%
ALT	C	0.37%
CELC	F	0.34%
GHRS	C	0.31%
AURA	C	0.3%
CMPS	F	0.23%
ACIU	D	0.22%
STRO	F	0.17%
ALDX	D	0.17%
ENTA	F	0.14%
INZY	F	0.12%
HLVX	F	0.06%

SBIO Underweight 125 Positions Relative to IBB

Symbol	Grade	Weight
GILD	C	-9.84%
VRTX	D	-8.0%
AMGN	F	-7.43%
REGN	F	-5.57%
IQV	F	-3.64%
ALNY	D	-3.14%
MTD	F	-2.57%
BIIB	F	-2.36%
ILMN	C	-2.25%
WAT	C	-2.15%
NTRA	A	-1.98%
UTHR	C	-1.66%
INCY	C	-1.41%
MRNA	F	-1.34%
INSM	C	-1.3%
NBIX	C	-1.24%
BMRN	F	-1.23%
TECH	F	-1.1%
EXEL	B	-1.01%
CRL	D	-1.0%
SRPT	F	-1.0%
PCVX	D	-0.98%
ITCI	C	-0.87%
MEDP	D	-0.84%
RVMD	C	-0.82%
RGEN	D	-0.7%
BPMC	B	-0.62%
CYTK	F	-0.61%
MDGL	B	-0.6%
HALO	F	-0.59%
ROIV	C	-0.53%
BRKR	D	-0.52%
ADMA	B	-0.49%
IONS	F	-0.48%
RARE	F	-0.41%
BHVN	D	-0.4%
CRSP	D	-0.4%
AXSM	B	-0.39%
RYTM	C	-0.34%
BBIO	F	-0.33%
NUVL	C	-0.32%
APLS	F	-0.31%
VCYT	B	-0.31%
SWTX	C	-0.27%
KYMR	D	-0.26%
TWST	F	-0.24%
ARWR	D	-0.23%
DYN	F	-0.23%
SRRK	C	-0.22%
IOVA	F	-0.21%
LGND	C	-0.21%
BEAM	D	-0.19%
JANX	C	-0.19%
FTRE	D	-0.18%
WVE	C	-0.18%
SMMT	D	-0.18%
APGE	F	-0.18%
DVAX	C	-0.17%
NVCR	C	-0.17%
GPCR	F	-0.16%
NRIX	C	-0.15%
MYGN	F	-0.14%
TVTX	C	-0.14%
RXRX	F	-0.14%
TXG	F	-0.14%
NVAX	F	-0.13%
ZYME	C	-0.13%
CDNA	D	-0.12%
RCKT	F	-0.12%
ARQT	B	-0.11%
KNSA	F	-0.09%
CTKB	C	-0.08%
CSTL	D	-0.08%
ELVN	D	-0.08%
ADPT	C	-0.07%
RLAY	F	-0.06%
MRVI	F	-0.06%
NUVB	C	-0.06%
VIR	D	-0.06%
PACB	F	-0.05%
CGEM	F	-0.05%
ABUS	D	-0.05%
OPK	C	-0.05%
TSHA	C	-0.04%
TERN	F	-0.04%
TRML	D	-0.04%
RVNC	F	-0.04%
QTRX	F	-0.04%
ORIC	F	-0.04%
HUMA	F	-0.04%
RGNX	D	-0.04%
VYGR	F	-0.03%
SAGE	F	-0.03%
QURE	C	-0.03%
KALV	F	-0.03%
SANA	F	-0.03%
VERV	F	-0.03%
SLRN	F	-0.03%
PHAT	F	-0.03%
MGTX	C	-0.03%
ACRS	B	-0.03%
MXCT	D	-0.03%
OKUR	F	-0.02%
PRME	F	-0.02%
CRBU	D	-0.02%
NAUT	F	-0.02%
BMEA	F	-0.02%
THRD	F	-0.02%
MGNX	F	-0.02%
ATAI	C	-0.02%
EDIT	F	-0.02%
AMLX	C	-0.02%
TNGX	F	-0.02%
AVIR	F	-0.02%
DNA	F	-0.02%
BLUE	F	-0.01%
OVID	F	-0.01%
CHRS	D	-0.01%
PGEN	F	-0.01%
VTYX	F	-0.01%
CABA	F	-0.01%
LYEL	F	-0.01%
MRNS	F	-0.0%
RAPT	F	-0.0%
ALXO	F	-0.0%

SBIO: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Specialty & Generic Medical Care Facilities