SBIO vs. BIS ETF Comparison
Comparison of ALPS Medical Breakthroughs ETF (SBIO) to ProShares UltraShort Nasdaq Biotechnology (BIS)
SBIO
ALPS Medical Breakthroughs ETF
SBIO Description
The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.
Grade (RS Rating)
Last Trade
$38.26
Average Daily Volume
6,572
83
BIS
ProShares UltraShort Nasdaq Biotechnology
BIS Description
The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.Grade (RS Rating)
Last Trade
$15.54
Average Daily Volume
13,954
73
Performance
| Period | SBIO | BIS |
|---|---|---|
| 30 Days | 1.91% | 1.97% |
| 60 Days | 2.27% | 8.40% |
| 90 Days | 7.65% | 1.66% |
| 12 Months | 52.91% | -33.52% |
15 Overlapping Holdings
| Symbol | Grade | Weight in SBIO | Weight in BIS | Overlap | |
|---|---|---|---|---|---|
| ACAD | F | 1.57% | 0.81% | 0.81% | |
| AGIO | B | 1.65% | 0.43% | 0.43% | |
| ALEC | D | 0.3% | 0.18% | 0.18% | |
| ALKS | F | 2.88% | 0.36% | 0.36% | |
| ALLO | D | 0.38% | 0.37% | 0.37% | |
| ARVN | C | 1.22% | 0.24% | 0.24% | |
| DNLI | C | 2.39% | 0.26% | 0.26% | |
| FOLD | B | 2.27% | 0.32% | 0.32% | |
| GLPG | F | 1.25% | 0.22% | 0.22% | |
| IRWD | F | 0.4% | 0.24% | 0.24% | |
| PTCT | B | 2.05% | 0.4% | 0.4% | |
| TBPH | C | 0.28% | 0.17% | 0.17% | |
| XNCR | A | 0.87% | 0.26% | 0.26% | |
| YMAB | A | 0.43% | 0.16% | 0.16% | |
| ZLAB | B | 2.11% | 0.24% | 0.24% |
SBIO Overweight 68 Positions Relative to BIS
| Symbol | Grade | Weight | |
|---|---|---|---|
| RNA | C | 3.38% | |
| KRYS | C | 3.33% | |
| CORT | B | 3.2% | |
| CRNX | B | 3.04% | |
| ACLX | B | 3.02% | |
| IMVT | F | 2.93% | |
| MRUS | C | 2.38% | |
| XENE | C | 2.03% | |
| EWTX | B | 2.03% | |
| VRNA | A | 1.83% | |
| PTGX | B | 1.77% | |
| CGON | F | 1.67% | |
| IDYA | F | 1.61% | |
| GERN | C | 1.55% | |
| VERA | A | 1.5% | |
| KROS | A | 1.41% | |
| VCEL | D | 1.35% | |
| LBPH | A | 1.34% | |
| AKRO | A | 1.3% | |
| MIRM | B | 1.25% | |
| CLDX | F | 1.21% | |
| MNKD | A | 1.14% | |
| BCRX | A | 1.1% | |
| SNDX | F | 1.07% | |
| IMCR | F | 1.06% | |
| RCUS | F | 1.04% | |
| NTLA | F | 1.03% | |
| TARS | A | 0.97% | |
| VRDN | B | 0.93% | |
| SPRY | B | 0.92% | |
| IRON | D | 0.9% | |
| KURA | F | 0.89% | |
| COGT | B | 0.89% | |
| DAWN | A | 0.85% | |
| PHVS | A | 0.77% | |
| APLT | A | 0.71% | |
| AUPH | A | 0.65% | |
| ANAB | F | 0.59% | |
| PRTA | F | 0.58% | |
| LQDA | C | 0.58% | |
| PLRX | A | 0.56% | |
| ETNB | D | 0.54% | |
| REPL | B | 0.53% | |
| ERAS | C | 0.48% | |
| ANNX | B | 0.47% | |
| OLMA | F | 0.46% | |
| MLYS | B | 0.44% | |
| CELC | D | 0.4% | |
| SVRA | D | 0.37% | |
| FLGT | C | 0.37% | |
| URGN | F | 0.35% | |
| ARCT | F | 0.35% | |
| AURA | B | 0.34% | |
| FULC | F | 0.34% | |
| ALT | D | 0.32% | |
| CMPS | F | 0.29% | |
| AVXL | A | 0.29% | |
| FDMT | F | 0.27% | |
| GHRS | D | 0.25% | |
| ALDX | D | 0.21% | |
| ACIU | F | 0.2% | |
| INZY | F | 0.19% | |
| STRO | D | 0.19% | |
| ITOS | F | 0.19% | |
| ENTA | D | 0.17% | |
| VNDA | D | 0.17% | |
| ZNTL | D | 0.15% | |
| HLVX | C | 0.06% |
SBIO Underweight 58 Positions Relative to BIS
| Symbol | Grade | Weight | |
|---|---|---|---|
| AMGN | C | -8.14% | |
| GILD | A | -7.41% | |
| VRTX | D | -7.21% | |
| BIIB | F | -6.12% | |
| ILMN | A | -5.67% | |
| REGN | F | -4.13% | |
| INCY | A | -2.09% | |
| BMRN | F | -1.91% | |
| ALNY | C | -1.6% | |
| VTRS | B | -1.35% | |
| SNY | D | -1.29% | |
| NBIX | C | -1.16% | |
| SRPT | D | -1.15% | |
| NVCR | F | -1.1% | |
| JAZZ | D | -1.03% | |
| TECH | B | -1.02% | |
| IONS | F | -1.02% | |
| GH | D | -0.96% | |
| AMRN | F | -0.85% | |
| MRNA | F | -0.83% | |
| BGNE | C | -0.83% | |
| ASND | F | -0.77% | |
| EXEL | A | -0.73% | |
| ARWR | F | -0.65% | |
| BLUE | F | -0.65% | |
| BBIO | D | -0.51% | |
| ALLK | B | -0.49% | |
| UTHR | A | -0.49% | |
| NKTR | C | -0.48% | |
| SAGE | F | -0.48% | |
| BPMC | C | -0.48% | |
| FGEN | F | -0.47% | |
| CRSP | C | -0.42% | |
| RARE | D | -0.42% | |
| ADPT | A | -0.42% | |
| MEDP | F | -0.4% | |
| ARGX | A | -0.4% | |
| AXSM | C | -0.38% | |
| GRFS | B | -0.36% | |
| IOVA | B | -0.36% | |
| KOD | B | -0.35% | |
| HALO | B | -0.35% | |
| QURE | B | -0.35% | |
| APLS | F | -0.31% | |
| MYGN | F | -0.26% | |
| INSM | D | -0.23% | |
| FATE | F | -0.23% | |
| PCRX | C | -0.22% | |
| ITCI | A | -0.21% | |
| RGNX | F | -0.21% | |
| ESPR | C | -0.19% | |
| EDIT | F | -0.19% | |
| LGND | A | -0.19% | |
| INVA | C | -0.18% | |
| VCYT | A | -0.18% | |
| CHRS | F | -0.16% | |
| HCM | C | -0.15% | |
| SUPN | B | -0.15% |
SBIO: Top Represented Industries & Keywords
BIS: Top Represented Industries & Keywords
Compare ETFs
