MEDX vs. BIS ETF Comparison

Comparison of Horizon Kinetics Medical ETF (MEDX) to ProShares UltraShort Nasdaq Biotechnology (BIS)
MEDX

Horizon Kinetics Medical ETF

MEDX Description

The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$27.81

Average Daily Volume

1,083

Number of Holdings *

32

* may have additional holdings in another (foreign) market
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$16.67

Average Daily Volume

13,744

Number of Holdings *

73

* may have additional holdings in another (foreign) market
Performance
Period MEDX BIS
30 Days -8.29% 7.34%
60 Days -10.35% 11.36%
90 Days -12.38% 16.52%
12 Months -2.56% -28.39%
11 Overlapping Holdings
Symbol Grade Weight in MEDX Weight in BIS Overlap
ALKS B 3.91% 0.36% 0.36%
ALLO F 0.28% 0.37% 0.28%
ALNY D 4.45% 1.6% 1.6%
AMGN D 5.96% 8.14% 5.96%
BIIB F 3.08% 6.12% 3.08%
BLUE F 0.08% 0.65% 0.08%
CRSP D 2.97% 0.42% 0.42%
EDIT F 0.53% 0.19% 0.19%
IONS F 2.78% 1.02% 1.02%
REGN F 3.38% 4.13% 3.38%
VTRS A 0.27% 1.35% 0.27%
MEDX Overweight 21 Positions Relative to BIS
Symbol Grade Weight
LLY F 15.83%
ABBV D 7.81%
BMY B 6.23%
NVS D 5.95%
AZN D 4.86%
JNJ D 4.65%
PFE D 4.04%
MRK F 3.96%
GSK F 2.32%
BCYC F 1.95%
BEAM D 1.51%
NTLA F 1.3%
REPL B 0.98%
GALT C 0.89%
HLN D 0.79%
VNDA C 0.79%
LTRN F 0.6%
GEHC F 0.48%
TSVT F 0.41%
PACB F 0.13%
MURA D 0.05%
MEDX Underweight 62 Positions Relative to BIS
Symbol Grade Weight
GILD C -7.41%
VRTX F -7.21%
ILMN D -5.67%
INCY C -2.09%
BMRN D -1.91%
SNY F -1.29%
NBIX C -1.16%
SRPT D -1.15%
NVCR C -1.1%
JAZZ B -1.03%
TECH D -1.02%
GH B -0.96%
AMRN F -0.85%
MRNA F -0.83%
BGNE D -0.83%
ACAD D -0.81%
ASND D -0.77%
EXEL B -0.73%
ARWR F -0.65%
BBIO F -0.51%
ALLK D -0.49%
UTHR C -0.49%
NKTR F -0.48%
SAGE F -0.48%
BPMC C -0.48%
FGEN D -0.47%
AGIO C -0.43%
RARE D -0.42%
ADPT C -0.42%
MEDP D -0.4%
PTCT B -0.4%
ARGX A -0.4%
AXSM B -0.38%
GRFS C -0.36%
IOVA F -0.36%
KOD C -0.35%
HALO F -0.35%
QURE D -0.35%
FOLD F -0.32%
APLS D -0.31%
XNCR B -0.26%
MYGN F -0.26%
DNLI D -0.26%
ZLAB C -0.24%
IRWD F -0.24%
ARVN D -0.24%
INSM C -0.23%
FATE F -0.23%
PCRX C -0.22%
GLPG D -0.22%
ITCI C -0.21%
RGNX F -0.21%
ESPR C -0.19%
LGND B -0.19%
INVA D -0.18%
VCYT B -0.18%
ALEC F -0.18%
TBPH C -0.17%
YMAB F -0.16%
CHRS D -0.16%
HCM D -0.15%
SUPN C -0.15%
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