HRTS vs. BIS ETF Comparison

Comparison of Tema Cardiovascular and Metabolic ETF (HRTS) to ProShares UltraShort Nasdaq Biotechnology (BIS)
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description

Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$33.20

Average Daily Volume

14,638

Number of Holdings *

36

* may have additional holdings in another (foreign) market
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$15.54

Average Daily Volume

13,954

Number of Holdings *

73

* may have additional holdings in another (foreign) market
Performance
Period HRTS BIS
30 Days -0.75% 1.97%
60 Days -6.06% 8.40%
90 Days -1.75% 1.66%
12 Months -33.52%
9 Overlapping Holdings
Symbol Grade Weight in HRTS Weight in BIS Overlap
ALNY C 5.47% 1.6% 1.6%
AMGN C 7.87% 8.14% 7.87%
ARWR F 1.58% 0.65% 0.65%
ASND F 2.06% 0.77% 0.77%
BBIO D 3.62% 0.51% 0.51%
IONS F 2.41% 1.02% 1.02%
RARE D 2.22% 0.42% 0.42%
REGN F 2.76% 4.13% 2.76%
VRTX D 4.96% 7.21% 4.96%
HRTS Overweight 27 Positions Relative to BIS
Symbol Grade Weight
LLY F 5.48%
CRNX B 3.79%
CYTK F 3.25%
MDT B 2.9%
MREO D 2.68%
MASI A 2.52%
BSX C 2.28%
NTLA F 2.11%
MIRM B 2.08%
RCKT F 2.07%
MLYS B 2.05%
PODD A 2.03%
DXCM C 1.99%
EW D 1.97%
KROS A 1.96%
NVS D 1.33%
AKRO A 1.19%
WST B 1.17%
SLN F 1.13%
VKTX A 1.07%
EWTX B 0.99%
MDGL A 0.95%
NARI A 0.84%
TERN D 0.72%
VERV C 0.64%
TNYA F 0.38%
RANI F 0.32%
HRTS Underweight 64 Positions Relative to BIS
Symbol Grade Weight
GILD A -7.41%
BIIB F -6.12%
ILMN A -5.67%
INCY A -2.09%
BMRN F -1.91%
VTRS B -1.35%
SNY D -1.29%
NBIX C -1.16%
SRPT D -1.15%
NVCR F -1.1%
JAZZ D -1.03%
TECH B -1.02%
GH D -0.96%
AMRN F -0.85%
MRNA F -0.83%
BGNE C -0.83%
ACAD F -0.81%
EXEL A -0.73%
BLUE F -0.65%
ALLK B -0.49%
UTHR A -0.49%
NKTR C -0.48%
SAGE F -0.48%
BPMC C -0.48%
FGEN F -0.47%
AGIO B -0.43%
CRSP C -0.42%
ADPT A -0.42%
MEDP F -0.4%
PTCT B -0.4%
ARGX A -0.4%
AXSM C -0.38%
ALLO D -0.37%
GRFS B -0.36%
IOVA B -0.36%
ALKS F -0.36%
KOD B -0.35%
HALO B -0.35%
QURE B -0.35%
FOLD B -0.32%
APLS F -0.31%
XNCR A -0.26%
MYGN F -0.26%
DNLI C -0.26%
ZLAB B -0.24%
IRWD F -0.24%
ARVN C -0.24%
INSM D -0.23%
FATE F -0.23%
PCRX C -0.22%
GLPG F -0.22%
ITCI A -0.21%
RGNX F -0.21%
ESPR C -0.19%
EDIT F -0.19%
LGND A -0.19%
INVA C -0.18%
VCYT A -0.18%
ALEC D -0.18%
TBPH C -0.17%
YMAB A -0.16%
CHRS F -0.16%
HCM C -0.15%
SUPN B -0.15%
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