BIS vs. HRTS ETF Comparison

Comparison of ProShares UltraShort Nasdaq Biotechnology (BIS) to Tema Cardiovascular and Metabolic ETF (HRTS)
BIS

ProShares UltraShort Nasdaq Biotechnology

BIS Description

The investment seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index®. The fund invests in derivatives that ProShare Advisors believes, in combination, should have similar daily return characteristics as two times the inverse (-2x) of the daily return of the index. The index is a modified capitalization weighted index that includes securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark ("ICB") which also meet other eligibility criteria determined by NASDAQ. It is non-diversified.

Grade (RS Rating)

Last Trade

$17.27

Average Daily Volume

5,046

Number of Holdings *

75

* may have additional holdings in another (foreign) market
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$33.00

Average Daily Volume

22,023

Number of Holdings *

10

* may have additional holdings in another (foreign) market
Performance
Period BIS HRTS
30 Days 0.65% 1.95%
60 Days -3.04% 2.26%
90 Days -8.43% 1.04%
12 Months -15.25%
2 Overlapping Holdings
Symbol Grade Weight in BIS Weight in HRTS Overlap
AMGN B 8.14% 5.54% 5.54%
VRTX B 7.21% 6.09% 6.09%
BIS Overweight 73 Positions Relative to HRTS
Symbol Grade Weight
GILD C 7.41%
BIIB C 6.12%
ILMN F 5.67%
REGN B 4.13%
INCY C 2.09%
BMRN D 1.91%
ALNY A 1.6%
VTRS F 1.35%
SNY B 1.29%
NBIX C 1.16%
SRPT C 1.15%
NVCR D 1.1%
JAZZ F 1.03%
TECH D 1.02%
IONS B 1.02%
GH C 0.96%
AMRN F 0.85%
MRNA D 0.83%
BGNE F 0.83%
ACAD D 0.81%
ASND C 0.77%
EXEL C 0.73%
ARWR C 0.65%
BLUE F 0.65%
BBIO D 0.51%
ALLK F 0.49%
UTHR B 0.49%
NKTR D 0.48%
SAGE F 0.48%
BPMC B 0.48%
FGEN F 0.47%
DCPH A 0.43%
AGIO C 0.43%
CRSP F 0.42%
RARE F 0.42%
ADPT D 0.42%
MEDP C 0.4%
PTCT D 0.4%
ARGX B 0.4%
AXSM B 0.38%
ALLO F 0.37%
GRFS F 0.36%
IOVA F 0.36%
ALKS D 0.36%
KOD F 0.35%
HALO B 0.35%
QURE F 0.35%
FOLD F 0.32%
APLS F 0.31%
XNCR F 0.26%
MYGN B 0.26%
DNLI C 0.26%
ZLAB F 0.24%
IRWD F 0.24%
ARVN F 0.24%
INSM C 0.23%
FATE F 0.23%
PCRX F 0.22%
GLPG F 0.22%
ITCI C 0.21%
RGNX F 0.21%
ESPR C 0.19%
EDIT F 0.19%
LGND B 0.19%
INVA B 0.18%
VCYT C 0.18%
ALEC F 0.18%
TBPH F 0.17%
YMAB D 0.16%
CHRS F 0.16%
HCM D 0.15%
NGM D 0.15%
SUPN F 0.15%
BIS Underweight 8 Positions Relative to HRTS
Symbol Grade Weight
LLY B -5.32%
NVO C -5.07%
DXCM F -3.95%
EW B -3.13%
NARI C -3.12%
PODD C -3.01%
MDT D -2.86%
MREO C -2.84%
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