SeaStar Medical Holding Corporation, a medical device company, develops cytopheresis systems for addressing inflammation-based diseases and conditions. The company focuses on acute renal failure, end-stage renal disease, and acute inflammation induced by cardiopulmonary bypass surgery. It develops products based on the configurations of commercially available hollow fiber dialysis filters that are used in a proprietary manner to sequester and deactivate leukocytes in the patient's blood system. The company was founded in 1994 and is based in Denver, Colorado.