22nd Century Group, Inc., a plant biotechnology company, focuses on tobacco harm reduction and smoking cessation products produced from modifying the nicotine content in tobacco plants through genetic engineering and plant breeding. It develops smoking cessation products for smokers who are unable or unwilling to quit smoking; and modified risk tobacco products that reduce exposure to certain tobacco smoke toxins compared to conventional cigarettes. The company's products include X-22, a prescription smoking cessation aid, which is a tobacco-based botanical medical product for use as a smoking cessation therapy; RED SUN and MAGIC regular and menthol cigarettes; and SPECTRUM government research cigarettes. It is also developing modified risk cigarettes, such as BRAND A, which has approximately 95% less nicotine than tobacco in cigarettes; and BRAND B cigarettes' with smoke that contains the lowest amount of tar per milligram of nicotine. 22nd Century Group, Inc. was founded in 1998 and is based in Clarence, New York.