Lysosomal Storage Disorders (LSDs) are a group of inherited metabolic disorders caused by the buildup of toxic materials in the lysosomes of cells. Lysosomes are organelles that contain enzymes that break down and recycle materials in the cell. When these enzymes are deficient or absent, toxic materials accumulate in the lysosomes, leading to cell damage and a wide range of symptoms. Symptoms of LSDs can include developmental delays, organ dysfunction, skeletal abnormalities, and neurological problems. Treatment for LSDs is often focused on managing symptoms and preventing further damage.