ASIC is an integrated circuit developed for a particular use, as opposed to a general-purpose device.
ASIC may also refer to:

Accreditation Service for International Colleges, an educational accreditation agency in the UK
Acid-sensing ion channels, a protein family
Air and Space Interoperability Council
Arfoire Syndicate of International Crime, the antagonist group in the video game Hyperdimension Neptunia Mk2
ASIC programming language, a dialect of BASIC
Associated Signature Containers (ASiC) specifies the use of container structures to bind together one or more signed objects with either advanced electronic signatures or time-stamp tokens into one single digital container.
Association for Science and Information on Coffee, see Andrea Illy
Australian Securities and Investments Commission, an independent Australian government body that acts as Australia's corporate regulator
Aviation Security Identification Card, an Australian identification card
Application-specific integrated circuit