Dystrophin Stocks List
Symbol | Grade | Name | % Change | |
---|---|---|---|---|
SLDB | F | Solid Biosciences Inc. | -1.68 | |
WVE | C | WAVE Life Sciences Ltd. | 2.82 | |
DYN | B | Dyne Therapeutics, Inc. | 0.91 |
Related Industries: Biotechnology Drug Manufacturers - Specialty & Generic
Symbol | Grade | Name | Weight | |
---|---|---|---|---|
IBRN | D | iShares Neuroscience and Healthcare ETF | 5.85 | |
PTH | B | Invesco DWA Healthcare Momentum ETF | 2.32 | |
BBC | D | Virtus LifeSci Biotech Clinical Trials ETF | 1.69 | |
BTEC | C | Principal Healthcare Innovators Index ETF | 0.8 | |
IWC | D | iShares Microcap ETF | 0.74 |
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- Dystrophin
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex (DAPC). Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere.
The DMD gene, encoding the dystrophin protein, is one of the longest human genes known, covering 2.3 megabases (0.08% of the human genome) at locus Xp21. The primary transcript in muscle measures about 2,100 kilobases and takes 16 hours to transcribe; the mature mRNA measures 14.0 kilobases. The 79-exon muscle transcript codes for a protein of 3685 amino acid residues.
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