Treatment of osteoarthritis typically involves a combination of lifestyle changes, medications, physical therapy, and in some cases, surgery. Lifestyle changes may include weight loss, exercise, and avoiding activities that put stress on the joints. Medications may include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs). Physical therapy can help to strengthen the muscles around the affected joint and improve range of motion. Surgery may be recommended in severe cases to repair or replace the joint.