Antiprogestogens Stocks List
Symbol | Grade | Name | % Change | |
---|---|---|---|---|
CORT | B | Corcept Therapeutics Incorporated | 0.02 | |
CNTX | F | Context Therapeutics Inc. | -4.29 |
Related Industries: Biotechnology
Symbol | Grade | Name | Weight | |
---|---|---|---|---|
PJP | D | PowerShares Dynamic Pharmaceuticals | 5.29 | |
XPH | B | SPDR S&P Pharmaceuticals ETF | 4.96 | |
FBT | D | First Trust Amex Biotech Index Fund | 4.07 | |
JSML | B | Janus Small Cap Growth Alpha ETF | 3.87 | |
SBIO | C | ALPS Medical Breakthroughs ETF | 3.66 |
Compare ETFs
Date | Stock | Title |
---|---|---|
Nov 20 | CORT | Wall Street Analysts Think Corcept (CORT) Could Surge 37.91%: Read This Before Placing a Bet |
- Antiprogestogens
Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body. They act by blocking the progesterone receptor (PR) and/or inhibiting or suppressing progestogen production. Antiprogestogens are one of three types of sex hormone antagonists, the others being antiestrogens and antiandrogens.Antiprogestogens are used as abortifacients and emergency contraceptives and in the treatment of uterine fibroids. They are also being studied in the treatment of breast cancer. Examples of antiprogestogens include the progesterone receptor weak partial agonist mifepristone, the selective progesterone receptor modulator (SPRM) ulipristal acetate, and the silent antagonist aglepristone. For medical abortion, mifepristone is combined with a prostaglandin (e.g., gemeprost).
Several hundred antiprogestogens have been developed, but only three, mifepristone, lilopristone, and onapristone, have been given to humans, and of these, only mifepristone has been approved and introduced for clinical use.
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