XBI vs. IBRN ETF Comparison

Comparison of SPDR S&P Biotech ETF (XBI) to iShares Neuroscience and Healthcare ETF (IBRN)
XBI

SPDR S&P Biotech ETF

XBI Description

The investment seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index. In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a replication strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology industry group of the S&P Total Market Index ("S&P TMI"). The fund is non-diversified.

Grade (RS Rating)

Last Trade

$91.83

Average Daily Volume

7,954,499

Number of Holdings *

128

* may have additional holdings in another (foreign) market
IBRN

iShares Neuroscience and Healthcare ETF

IBRN Description iShares Neuroscience and Healthcare ETF is an exchange traded fund launched by BlackRock, Inc. It is managed by BlackRock Fund Advisors. The fund invests in public equity markets of global region. It invests in stocks of companies operating across neurology biopharmaceuticals or neurological devices sectors. The fund invests in growth and value stocks of companies across diversified market capitalization. It seeks to track the performance of the NYSE FactSet Global Neuro Biopharma and MedTech Index, by using representative sampling technique. iShares Neuroscience and Healthcare ETF is domiciled in the United States.

Grade (RS Rating)

Last Trade

$25.89

Average Daily Volume

316

Number of Holdings *

45

* may have additional holdings in another (foreign) market
Performance
Period XBI IBRN
30 Days -8.40% -5.38%
60 Days -9.32% 5.36%
90 Days -6.06% 2.59%
12 Months 31.15% 26.71%
13 Overlapping Holdings
Symbol Grade Weight in XBI Weight in IBRN Overlap
ACAD C 0.7% 3.72% 0.7%
ALEC F 0.06% 0.73% 0.06%
ALKS B 1.06% 3.63% 1.06%
ANNX D 0.19% 1.01% 0.19%
AVXL C 0.15% 1.26% 0.15%
BIIB F 2.16% 2.91% 2.16%
CPRX C 0.41% 4.08% 0.41%
DYN F 0.69% 2.91% 0.69%
NBIX D 2.46% 3.54% 2.46%
PRTA F 0.16% 1.37% 0.16%
PTCT B 0.62% 4.75% 0.62%
SRPT F 2.35% 3.19% 2.35%
SRRK C 0.48% 3.17% 0.48%
XBI Overweight 115 Positions Relative to IBRN
Symbol Grade Weight
INCY B 3.15%
UTHR B 2.88%
GILD B 2.87%
VKTX F 2.51%
ABBV F 2.51%
VRTX C 2.51%
NTRA B 2.5%
ALNY D 2.49%
AMGN D 2.35%
INSM D 2.33%
MDGL C 2.27%
EXAS F 1.97%
BMRN F 1.91%
MRNA F 1.79%
REGN F 1.74%
CYTK D 1.71%
BPMC D 1.7%
HALO D 1.59%
CRSP D 1.59%
RVMD B 1.42%
RNA C 1.36%
TGTX B 1.36%
KRYS D 1.22%
IOVA D 1.15%
EXEL B 1.14%
ADMA C 1.11%
ROIV D 1.11%
IONS F 1.1%
PCVX D 0.95%
TWST F 0.91%
BBIO F 0.9%
GERN F 0.88%
CRNX C 0.84%
APLS F 0.84%
ACLX C 0.79%
AGIO B 0.71%
RARE F 0.71%
BEAM D 0.7%
RXRX F 0.67%
SWTX C 0.66%
IMVT D 0.65%
FOLD F 0.64%
PTGX D 0.61%
NTLA F 0.59%
RYTM C 0.59%
NUVL D 0.58%
VERA B 0.56%
ARWR D 0.55%
IDYA F 0.54%
ARDX F 0.54%
SNDX D 0.53%
JANX C 0.51%
DNLI C 0.5%
MIRM A 0.5%
NVAX F 0.49%
VCYT B 0.48%
KYMR C 0.47%
AKRO C 0.45%
DVAX C 0.45%
CGON D 0.44%
BCRX D 0.41%
ARQT D 0.41%
KROS C 0.4%
VCEL A 0.39%
NRIX C 0.37%
CLDX F 0.35%
SMMT D 0.33%
MNKD B 0.33%
IRON C 0.33%
RCKT F 0.32%
VRDN C 0.32%
DAWN D 0.31%
MYGN F 0.28%
IRWD D 0.27%
CGEM F 0.26%
VIR C 0.24%
EBS C 0.23%
TVTX B 0.23%
CDNA D 0.23%
KURA F 0.23%
APLT C 0.22%
XNCR B 0.21%
RCUS F 0.2%
CDMO A 0.2%
HUMA F 0.19%
SPRY C 0.19%
VERV D 0.19%
ARCT F 0.18%
REPL C 0.18%
ETNB D 0.18%
ALT C 0.17%
IMNM F 0.16%
STOK D 0.16%
RLAY F 0.16%
OLMA F 0.16%
COGT D 0.16%
SAGE F 0.14%
SANA F 0.14%
ALLO D 0.14%
CELC F 0.13%
MDXG A 0.12%
ANAB F 0.12%
RGNX F 0.12%
OCGN F 0.12%
CCCC F 0.12%
FDMT F 0.11%
SVRA F 0.1%
ERAS C 0.1%
ORIC D 0.09%
YMAB D 0.08%
FATE F 0.08%
ITOS F 0.07%
KALV F 0.07%
SCLX F 0.07%
ABUS D 0.06%
XBI Underweight 32 Positions Relative to IBRN
Symbol Grade Weight
BHVN C -4.9%
ITCI B -4.2%
XENE D -3.95%
EWTX C -3.53%
AXNX A -3.46%
LBPH A -3.33%
SUPN B -3.22%
IART C -2.69%
AVDL F -2.4%
PRAX C -2.12%
SAVA C -1.9%
NGNE D -1.17%
DNTH D -0.97%
CAPR B -0.97%
SGMO C -0.95%
AXGN D -0.87%
RAPP C -0.8%
ZVRA B -0.78%
TRDA B -0.71%
LRMR D -0.55%
VYGR F -0.54%
VNDA C -0.48%
AMLX C -0.46%
CLPT D -0.46%
CTNM C -0.43%
ABEO C -0.42%
TSHA D -0.39%
SLDB F -0.32%
NVRO F -0.29%
ABOS D -0.25%
PEPG F -0.21%
ANRO F -0.16%
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