SBIO vs. LABU ETF Comparison

Comparison of ALPS Medical Breakthroughs ETF (SBIO) to Direxion Daily S&P Biotech Bull 3X Shares (LABU)
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description

The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$38.26

Average Daily Volume

6,572

Number of Holdings *

83

* may have additional holdings in another (foreign) market
LABU

Direxion Daily S&P Biotech Bull 3X Shares

LABU Description The investment seeks daily investment results, of 300% of the performance of the S&P Biotechnology Select Industry Index ("index"). The index is provided by S&P and includes domestic companies from the biotechnology industry. The fund normally creates long positions by investing at least 80% of its assets in the securities that comprise the index and/or financial instruments that provide leveraged and unleveraged exposure to the index. These financial instruments include: swap agreements; options on securities and indices; forward contracts; reverse repurchase agreements; ETFs; and other financial instruments. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$127.71

Average Daily Volume

886,307

Number of Holdings *

128

* may have additional holdings in another (foreign) market
Performance
Period SBIO LABU
30 Days 1.91% 1.73%
60 Days 2.27% -9.46%
90 Days 7.65% 2.64%
12 Months 52.91% 116.74%
52 Overlapping Holdings
Symbol Grade Weight in SBIO Weight in LABU Overlap
ACAD F 1.57% 0.4% 0.4%
ACLX B 3.02% 0.47% 0.47%
AGIO B 1.65% 0.39% 0.39%
AKRO A 1.3% 0.25% 0.25%
ALEC D 0.3% 0.03% 0.03%
ALKS F 2.88% 0.67% 0.67%
ALLO D 0.38% 0.08% 0.08%
ALT D 0.32% 0.1% 0.1%
ANAB F 0.59% 0.12% 0.12%
ANNX B 0.47% 0.13% 0.13%
APLT A 0.71% 0.14% 0.14%
ARCT F 0.35% 0.12% 0.12%
AVXL A 0.29% 0.07% 0.07%
BCRX A 1.1% 0.3% 0.3%
CELC D 0.4% 0.09% 0.09%
CGON F 1.67% 0.28% 0.28%
CLDX F 1.21% 0.25% 0.25%
COGT B 0.89% 0.13% 0.13%
CRNX B 3.04% 0.56% 0.56%
DAWN A 0.85% 0.19% 0.19%
DNLI C 2.39% 0.3% 0.3%
ERAS C 0.48% 0.06% 0.06%
ETNB D 0.54% 0.1% 0.1%
FDMT F 0.27% 0.07% 0.07%
FOLD B 2.27% 0.47% 0.47%
GERN C 1.55% 0.56% 0.56%
IDYA F 1.61% 0.36% 0.36%
IMVT F 2.93% 0.45% 0.45%
IRON D 0.9% 0.17% 0.17%
IRWD F 0.4% 0.15% 0.15%
ITOS F 0.19% 0.04% 0.04%
KROS A 1.41% 0.24% 0.24%
KRYS C 3.33% 0.79% 0.79%
KURA F 0.89% 0.16% 0.16%
MIRM B 1.25% 0.33% 0.33%
MNKD A 1.14% 0.2% 0.2%
NTLA F 1.03% 0.4% 0.4%
OLMA F 0.46% 0.1% 0.1%
PRTA F 0.58% 0.1% 0.1%
PTCT B 2.05% 0.41% 0.41%
PTGX B 1.77% 0.41% 0.41%
RCUS F 1.04% 0.15% 0.15%
REPL B 0.53% 0.12% 0.12%
RNA C 3.38% 0.88% 0.88%
SNDX F 1.07% 0.32% 0.32%
SPRY B 0.92% 0.12% 0.12%
SVRA D 0.37% 0.05% 0.05%
VCEL D 1.35% 0.23% 0.23%
VERA A 1.5% 0.31% 0.31%
VRDN B 0.93% 0.21% 0.21%
XNCR A 0.87% 0.13% 0.13%
YMAB A 0.43% 0.05% 0.05%
SBIO Overweight 31 Positions Relative to LABU
Symbol Grade Weight
CORT B 3.2%
MRUS C 2.38%
ZLAB B 2.11%
XENE C 2.03%
EWTX B 2.03%
VRNA A 1.83%
LBPH A 1.34%
GLPG F 1.25%
ARVN C 1.22%
IMCR F 1.06%
TARS A 0.97%
PHVS A 0.77%
AUPH A 0.65%
LQDA C 0.58%
PLRX A 0.56%
MLYS B 0.44%
FLGT C 0.37%
URGN F 0.35%
AURA B 0.34%
FULC F 0.34%
CMPS F 0.29%
TBPH C 0.28%
GHRS D 0.25%
ALDX D 0.21%
ACIU F 0.2%
INZY F 0.19%
STRO D 0.19%
ENTA D 0.17%
VNDA D 0.17%
ZNTL D 0.15%
HLVX C 0.06%
SBIO Underweight 76 Positions Relative to LABU
Symbol Grade Weight
ALNY C -1.83%
VKTX A -1.82%
EXAS A -1.78%
GILD A -1.78%
SRPT D -1.76%
UTHR A -1.71%
INCY A -1.7%
ABBV A -1.62%
VRTX D -1.61%
INSM D -1.59%
NBIX C -1.57%
AMGN C -1.57%
BIIB F -1.56%
NTRA B -1.56%
BMRN F -1.37%
REGN F -1.34%
MRNA F -1.28%
CYTK F -1.1%
CRSP C -1.0%
BPMC C -0.95%
HALO B -0.9%
MDGL A -0.89%
RVMD A -0.78%
TGTX A -0.77%
ROIV D -0.76%
IONS F -0.75%
PCVX C -0.71%
IOVA B -0.67%
EXEL A -0.61%
ADMA B -0.61%
BBIO D -0.58%
TWST F -0.55%
APLS F -0.55%
RARE D -0.53%
DYN F -0.5%
RXRX F -0.42%
BEAM F -0.4%
NUVL D -0.39%
SWTX D -0.39%
NVAX F -0.36%
ARWR F -0.35%
ARDX D -0.34%
JANX A -0.34%
SRRK B -0.33%
KYMR C -0.31%
RYTM D -0.31%
VCYT A -0.29%
DVAX A -0.28%
CPRX A -0.26%
MYGN F -0.24%
ARQT D -0.23%
NRIX B -0.23%
RCKT F -0.22%
SMMT C -0.21%
CGEM F -0.18%
TVTX B -0.16%
CDNA D -0.15%
HUMA D -0.14%
VIR B -0.13%
EBS B -0.13%
VERV C -0.12%
SANA F -0.12%
RLAY F -0.11%
CDMO C -0.11%
SAGE F -0.11%
STOK C -0.1%
IMNM F -0.1%
CCCC F -0.08%
OCGN F -0.07%
RGNX F -0.07%
SCLX D -0.06%
FATE F -0.06%
MDXG C -0.06%
ABUS D -0.05%
KALV D -0.05%
ORIC D -0.05%
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