OZEM vs. THNR ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Amplify Weight Loss Drug & Treatment ETF (THNR)

OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.37

Average Daily Volume

38,199

Number of Holdings ^*

14

* may have additional holdings in another (foreign) market

THNR

Amplify Weight Loss Drug & Treatment ETF

THNR Description

The fund's manager invests at least 80% of its net assets (plus borrowings for investment purposes) in securities that comprise the index. The index is comprised of global companies who are manufacturers in the GLP-1 agonist pharmaceutical business or who enable such business. GLP-1 agonists (glucagon-like peptide) seek to lower blood sugar levels and reduce appetite and promote fullness, with the ultimate potential for weight loss. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$23.22

Average Daily Volume

2,604

Number of Holdings ^*

15

* may have additional holdings in another (foreign) market

Performance

Period	OZEM	THNR
30 Days	-10.50%	-11.49%
60 Days	-10.19%	-15.44%
90 Days	-10.75%	-16.31%
12 Months

9 Overlapping Holdings

	Symbol	Grade	Weight in OZEM	Weight in THNR	Overlap
	ALT	C	4.44%	0.27%	0.27%
	AMGN	D	3.26%	5.07%	3.26%
	AZN	F	3.99%	4.62%	3.99%
	LLY	F	14.13%	14.71%	14.13%
	NVO	D	17.04%	13.16%	13.16%
	OPK	B	1.72%	0.21%	0.21%
	PFE	F	3.07%	5.03%	3.07%
	TERN	F	1.97%	0.14%	0.14%
	VKTX	F	3.39%	2.58%	2.58%

OZEM Overweight 5 Positions Relative to THNR

	Symbol	Grade	Weight
	SRRK	B	2.8%
	REGN	F	2.4%
	RYTM	C	2.3%
	TAK	D	2.17%
	CORT	B	1.77%

OZEM Underweight 6 Positions Relative to THNR

	Symbol	Grade	Weight
	TMO	D	-4.93%
	MRK	F	-4.79%
	WST	C	-4.49%
	TEVA	C	-3.68%
	CTLT	D	-2.0%
	HIMS	C	-0.83%

OZEM: Top Represented Industries & Keywords

Industries: Biotechnology Drug Manufacturers - Major Drug Manufacturers - Specialty & Generic

Keywords: Biopharmaceutical Obesity Pharmaceutical Products Cancer Inflammation Biotechnology Diabetes Medicine Neuroscience S&P 500 Alzheimer's Disease Anemia Asthma Cholesterol Depressive Disorder Hormones Hypertension Life Sciences Major Depressive Disorder Medication

THNR: Top Represented Industries & Keywords

Industries: Drug Manufacturers - Major Biotechnology Drug Manufacturers - Specialty & Generic Conglomerates Diagnostics & Research Medical Instruments & Supplies

Keywords: Obesity Pharmaceutical Products S&P 500 Medicine Biopharmaceutical Cancer Asthma Diabetes Inflammation Medication Neuroscience Alzheimer's Disease Animal Health Antibiotics Biotechnology Cholesterol Depressive Disorder Drugs Health Products Hormones