OZEM vs. LABU ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Direxion Daily S&P Biotech Bull 3X Shares (LABU)
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.91

Average Daily Volume

37,536

Number of Holdings *

14

* may have additional holdings in another (foreign) market
LABU

Direxion Daily S&P Biotech Bull 3X Shares

LABU Description The investment seeks daily investment results, of 300% of the performance of the S&P Biotechnology Select Industry Index ("index"). The index is provided by S&P and includes domestic companies from the biotechnology industry. The fund normally creates long positions by investing at least 80% of its assets in the securities that comprise the index and/or financial instruments that provide leveraged and unleveraged exposure to the index. These financial instruments include: swap agreements; options on securities and indices; forward contracts; reverse repurchase agreements; ETFs; and other financial instruments. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$113.42

Average Daily Volume

1,097,096

Number of Holdings *

128

* may have additional holdings in another (foreign) market
Performance
Period OZEM LABU
30 Days -7.33% -4.54%
60 Days -7.73% -13.12%
90 Days -10.10% -20.34%
12 Months 64.67%
6 Overlapping Holdings
Symbol Grade Weight in OZEM Weight in LABU Overlap
ALT C 4.44% 0.13% 0.13%
AMGN D 3.26% 1.5% 1.5%
REGN F 2.4% 1.14% 1.14%
RYTM C 2.3% 0.38% 0.38%
SRRK B 2.8% 0.32% 0.32%
VKTX F 3.39% 1.35% 1.35%
OZEM Overweight 8 Positions Relative to LABU
Symbol Grade Weight
NVO D 17.04%
LLY F 14.13%
AZN D 3.99%
PFE D 3.07%
TAK F 2.17%
TERN F 1.97%
CORT B 1.77%
OPK C 1.72%
OZEM Underweight 122 Positions Relative to LABU
Symbol Grade Weight
INCY C -2.06%
NTRA B -2.02%
UTHR C -1.92%
GILD C -1.88%
NBIX C -1.7%
VRTX F -1.68%
ALNY D -1.64%
INSM C -1.61%
SRPT D -1.48%
ABBV D -1.47%
BIIB F -1.42%
MDGL B -1.35%
EXAS D -1.31%
BMRN D -1.3%
CYTK F -1.17%
BPMC C -1.12%
TGTX B -1.05%
HALO F -1.0%
CRSP D -1.0%
RNA D -0.99%
MRNA F -0.98%
RVMD C -0.96%
KRYS B -0.81%
ADMA B -0.79%
EXEL B -0.77%
ROIV C -0.76%
IONS F -0.74%
ALKS B -0.72%
PCVX D -0.6%
CRNX C -0.58%
BBIO F -0.58%
APLS D -0.57%
IOVA F -0.56%
TWST D -0.54%
GERN D -0.53%
ACLX C -0.53%
DYN F -0.5%
SWTX C -0.5%
BEAM D -0.49%
AGIO C -0.49%
ACAD D -0.48%
RXRX F -0.47%
RARE D -0.47%
IMVT F -0.43%
PTCT B -0.43%
FOLD F -0.41%
VERA B -0.39%
MIRM B -0.39%
ARWR F -0.38%
NUVL D -0.38%
NTLA F -0.38%
PTGX C -0.37%
IDYA F -0.37%
DVAX C -0.35%
DNLI D -0.33%
VCYT B -0.33%
JANX C -0.33%
KYMR D -0.3%
SNDX F -0.29%
BCRX D -0.28%
CGON F -0.28%
ARDX F -0.28%
VCEL B -0.28%
AKRO B -0.27%
NVAX F -0.27%
ARQT C -0.27%
CPRX C -0.26%
KROS D -0.25%
NRIX D -0.25%
CLDX F -0.23%
MNKD C -0.22%
IRON B -0.22%
SMMT D -0.21%
VRDN D -0.2%
RCKT F -0.19%
DAWN F -0.19%
TVTX B -0.17%
MYGN F -0.17%
CGEM F -0.17%
IRWD F -0.16%
CDNA D -0.15%
VIR D -0.15%
XNCR B -0.15%
KURA F -0.15%
CDMO B -0.14%
APLT B -0.14%
RCUS F -0.13%
EBS C -0.13%
HUMA F -0.12%
ARCT F -0.12%
COGT D -0.11%
ETNB C -0.11%
ANNX F -0.11%
AVXL B -0.11%
VERV F -0.11%
SPRY D -0.11%
STOK F -0.11%
REPL B -0.11%
IMNM F -0.1%
PRTA F -0.1%
RLAY F -0.1%
MDXG B -0.1%
RGNX F -0.09%
OLMA F -0.09%
ALLO F -0.08%
ANAB F -0.08%
OCGN F -0.08%
CELC F -0.08%
SAGE F -0.08%
SANA F -0.08%
ERAS C -0.07%
CCCC F -0.07%
FDMT F -0.07%
ORIC F -0.06%
SCLX F -0.05%
SVRA D -0.05%
ALEC F -0.04%
YMAB F -0.04%
ABUS D -0.04%
ITOS F -0.04%
KALV D -0.04%
FATE F -0.04%
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