OZEM vs. HRTS ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Tema Cardiovascular and Metabolic ETF (HRTS)
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.29

Average Daily Volume

37,622

Number of Holdings *

14

* may have additional holdings in another (foreign) market
HRTS

Tema Cardiovascular and Metabolic ETF

HRTS Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from products or services related to the treatment of cardiovascular diseases and/or metabolic diseases, as defined by the Centers for Diseases Control and Preventions. The fund advisor generally is expected to consist of more than 15 companies but not more than 100 companies. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$30.77

Average Daily Volume

14,144

Number of Holdings *

36

* may have additional holdings in another (foreign) market
Performance
Period OZEM HRTS
30 Days -10.60% -9.25%
60 Days -11.17% -11.27%
90 Days -12.25% -12.29%
12 Months 15.50%
5 Overlapping Holdings
Symbol Grade Weight in OZEM Weight in HRTS Overlap
AMGN F 3.26% 5.11% 3.26%
LLY F 14.13% 6.44% 6.44%
REGN F 2.4% 2.37% 2.37%
TERN F 1.97% 0.7% 0.7%
VKTX F 3.39% 1.14% 1.14%
OZEM Overweight 9 Positions Relative to HRTS
Symbol Grade Weight
NVO F 17.04%
ALT C 4.44%
AZN F 3.99%
PFE F 3.07%
SRRK C 2.8%
RYTM C 2.3%
TAK D 2.17%
CORT B 1.77%
OPK C 1.72%
OZEM Underweight 31 Positions Relative to HRTS
Symbol Grade Weight
VRTX D -5.64%
ALNY D -4.95%
CRNX C -4.0%
BBIO F -3.69%
CYTK F -3.47%
BSX A -2.99%
ASND F -2.88%
MDT D -2.79%
MIRM B -2.6%
DXCM C -2.57%
MREO F -2.49%
IONS F -2.42%
MASI B -2.39%
KROS D -2.1%
EW C -1.91%
MLYS F -1.89%
PODD C -1.88%
RCKT F -1.8%
ARWR D -1.76%
RARE F -1.71%
NTLA F -1.66%
MDGL B -1.46%
WST C -1.43%
AKRO B -1.28%
NVS F -1.26%
NARI C -0.97%
EWTX C -0.96%
SLN F -0.91%
VERV F -0.64%
TNYA D -0.43%
RANI F -0.31%
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