OZEM vs. CANC ETF Comparison

Comparison of Roundhill GLP-1 & Weight Loss ETF (OZEM) to Tema Oncology ETF (CANC)
OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.29

Average Daily Volume

37,622

Number of Holdings *

14

* may have additional holdings in another (foreign) market
CANC

Tema Oncology ETF

CANC Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from oncology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$26.52

Average Daily Volume

2,676

Number of Holdings *

43

* may have additional holdings in another (foreign) market
Performance
Period OZEM CANC
30 Days -10.60% -6.12%
60 Days -11.17% -9.26%
90 Days -12.25% -11.21%
12 Months 15.05%
3 Overlapping Holdings
Symbol Grade Weight in OZEM Weight in CANC Overlap
AMGN F 3.26% 2.37% 2.37%
REGN F 2.4% 5.25% 2.4%
TERN F 1.97% 0.6% 0.6%
OZEM Overweight 11 Positions Relative to CANC
Symbol Grade Weight
NVO F 17.04%
LLY F 14.13%
ALT C 4.44%
AZN F 3.99%
VKTX F 3.39%
PFE F 3.07%
SRRK C 2.8%
RYTM C 2.3%
TAK D 2.17%
CORT B 1.77%
OPK C 1.72%
OZEM Underweight 40 Positions Relative to CANC
Symbol Grade Weight
GILD C -5.49%
RVMD C -4.6%
ARGX B -4.19%
ILMN C -4.16%
INCY C -4.1%
BPMC B -4.05%
EXEL B -2.93%
MRK D -2.81%
AGIO C -2.71%
MREO F -2.54%
BGNE D -2.3%
CRSP D -2.3%
SWTX C -2.14%
GH B -2.07%
NVS F -2.03%
NUVL C -1.99%
DAWN D -1.9%
GMAB F -1.84%
NTLA F -1.58%
ACLX C -1.5%
EXAS D -1.45%
CLDX F -1.44%
SDGR C -1.44%
JANX C -1.43%
LEGN D -1.41%
MRUS F -1.37%
LNTH D -1.22%
NRIX C -1.15%
COGT D -0.95%
IDYA F -0.9%
BNTX C -0.89%
BCYC F -0.84%
CGEM F -0.83%
ORIC F -0.76%
MRNA F -0.72%
RLAY F -0.69%
IMCR D -0.69%
RCUS F -0.67%
CGON F -0.56%
ARVN F -0.46%
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