MEDX vs. SBIO ETF Comparison

Comparison of Horizon Kinetics Medical ETF (MEDX) to ALPS Medical Breakthroughs ETF (SBIO)
MEDX

Horizon Kinetics Medical ETF

MEDX Description

The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$29.27

Average Daily Volume

512

Number of Holdings *

32

* may have additional holdings in another (foreign) market
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$38.26

Average Daily Volume

6,572

Number of Holdings *

83

* may have additional holdings in another (foreign) market
Performance
Period MEDX SBIO
30 Days -4.20% 1.91%
60 Days -8.31% 2.27%
90 Days -4.39% 7.65%
12 Months 4.75% 52.91%
5 Overlapping Holdings
Symbol Grade Weight in MEDX Weight in SBIO Overlap
ALKS F 3.44% 2.88% 2.88%
ALLO D 0.29% 0.38% 0.29%
NTLA F 1.17% 1.03% 1.03%
REPL B 0.99% 0.53% 0.53%
VNDA D 0.67% 0.17% 0.17%
MEDX Overweight 27 Positions Relative to SBIO
Symbol Grade Weight
LLY F 16.14%
ABBV A 8.78%
AMGN C 6.01%
NVS D 5.98%
BMY A 5.3%
AZN F 5.15%
JNJ D 4.65%
ALNY C 4.6%
PFE D 4.19%
MRK F 3.99%
REGN F 3.77%
BIIB F 3.21%
CRSP C 2.87%
IONS F 2.78%
GSK F 2.36%
BCYC D 1.96%
BEAM F 1.22%
HLN D 0.78%
GALT F 0.77%
EDIT F 0.54%
LTRN F 0.53%
GEHC D 0.48%
TSVT D 0.45%
VTRS B 0.24%
PACB C 0.14%
BLUE F 0.1%
MURA D 0.05%
MEDX Underweight 78 Positions Relative to SBIO
Symbol Grade Weight
RNA C -3.38%
KRYS C -3.33%
CORT B -3.2%
CRNX B -3.04%
ACLX B -3.02%
IMVT F -2.93%
DNLI C -2.39%
MRUS C -2.38%
FOLD B -2.27%
ZLAB B -2.11%
PTCT B -2.05%
XENE C -2.03%
EWTX B -2.03%
VRNA A -1.83%
PTGX B -1.77%
CGON F -1.67%
AGIO B -1.65%
IDYA F -1.61%
ACAD F -1.57%
GERN C -1.55%
VERA A -1.5%
KROS A -1.41%
VCEL D -1.35%
LBPH A -1.34%
AKRO A -1.3%
MIRM B -1.25%
GLPG F -1.25%
ARVN C -1.22%
CLDX F -1.21%
MNKD A -1.14%
BCRX A -1.1%
SNDX F -1.07%
IMCR F -1.06%
RCUS F -1.04%
TARS A -0.97%
VRDN B -0.93%
SPRY B -0.92%
IRON D -0.9%
KURA F -0.89%
COGT B -0.89%
XNCR A -0.87%
DAWN A -0.85%
PHVS A -0.77%
APLT A -0.71%
AUPH A -0.65%
ANAB F -0.59%
PRTA F -0.58%
LQDA C -0.58%
PLRX A -0.56%
ETNB D -0.54%
ERAS C -0.48%
ANNX B -0.47%
OLMA F -0.46%
MLYS B -0.44%
YMAB A -0.43%
IRWD F -0.4%
CELC D -0.4%
SVRA D -0.37%
FLGT C -0.37%
URGN F -0.35%
ARCT F -0.35%
AURA B -0.34%
FULC F -0.34%
ALT D -0.32%
ALEC D -0.3%
CMPS F -0.29%
AVXL A -0.29%
TBPH C -0.28%
FDMT F -0.27%
GHRS D -0.25%
ALDX D -0.21%
ACIU F -0.2%
INZY F -0.19%
STRO D -0.19%
ITOS F -0.19%
ENTA D -0.17%
ZNTL D -0.15%
HLVX C -0.06%
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