IHE vs. OZEM ETF Comparison

Comparison of iShares U.S. Pharmaceutical ETF (IHE) to Roundhill GLP-1 & Weight Loss ETF (OZEM)

IHE

iShares U.S. Pharmaceutical ETF

IHE Description

The investment seeks to track the investment results of an index composed of U.S. equities in the pharmaceuticals sector. The fund generally invests at least 90% of its assets in securities of the underlying index and in depositary receipts representing securities of the underlying index. It seeks to track the investment results of the Dow Jones U.S. Select Pharmaceuticals Index (the "underlying index"), which measures the performance of the pharmaceuticals sector of the U.S. equity market. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$67.20

Average Daily Volume

34,586

Number of Holdings ^*

10

* may have additional holdings in another (foreign) market

OZEM

Roundhill GLP-1 & Weight Loss ETF

OZEM Description

OZEM targets the global weight management industry. The fund invests in companies involved in the development of GLP-1 and other weight loss drugs. GLP-1 agonists seek to aid in weight management by lowering blood sugar levels, reducing appetite, and promoting fullness. The portfolio consists of firms with GLP-1 and weight loss drugs that have been approved by or are currently undergoing Phase I, Phase II, and/or Phase III clinical trials of the US Food & Drug Administration (FDA), or any applicable food and drug regulator for non-US companies. The portfolio is constructed using a proprietary methodology, which selects companies with high levels of thematic relevance based on research of each companys public filings and disclosures. In addition, eligible securities must meet minimum market-cap and liquidity requirements. The actively managed fund, although rebalances portfolio weighting on at least a quarterly basis, may have a heavy concentration on a few names.

Grade (RS Rating)

Last Trade

$25.45

Average Daily Volume

38,199

Number of Holdings ^*

14

* may have additional holdings in another (foreign) market

Performance

Period	IHE	OZEM
30 Days	-4.82%	-10.50%
60 Days	-5.55%	-10.19%
90 Days	-4.97%	-10.75%
12 Months	17.96%

2 Overlapping Holdings

	Symbol	Grade	Weight in IHE	Weight in OZEM	Overlap
	LLY	F	20.67%	14.13%	14.13%
	PFE	F	4.38%	3.07%	3.07%

IHE Overweight 8 Positions Relative to OZEM

	Symbol	Grade	Weight
	JNJ	D	22.25%
	BMY	B	5.27%
	VTRS	A	4.69%
	ZTS	D	4.32%
	CTLT	D	4.23%
	RPRX	D	4.18%
	MRK	F	4.09%
	ITCI	B	3.33%

IHE Underweight 12 Positions Relative to OZEM

	Symbol	Grade	Weight
	NVO	D	-17.04%
	ALT	C	-4.44%
	AZN	F	-3.99%
	VKTX	F	-3.39%
	AMGN	D	-3.26%
	SRRK	B	-2.8%
	REGN	F	-2.4%
	RYTM	C	-2.3%
	TAK	D	-2.17%
	TERN	F	-1.97%
	CORT	B	-1.77%
	OPK	B	-1.72%

IHE: Top Represented Industries & Keywords

Industries: Drug Manufacturers - Major Drug Manufacturers - Specialty & Generic Biotechnology

Keywords: S&P 500 Pharmaceutical Products Animal Health Biopharmaceutical Depressive Disorder Alzheimer's Disease Biotechnology Diabetes Dysfunction Health Products Hypertension Infectious Diseases Major Depressive Disorder Medication Neuroscience Schizophrenia Animal Health Products Anti Infectives Antibiotics Biopharmaceutical Products

OZEM: Top Represented Industries & Keywords

Industries: Biotechnology Drug Manufacturers - Major Drug Manufacturers - Specialty & Generic

Keywords: Biopharmaceutical Obesity Pharmaceutical Products Cancer Inflammation Biotechnology Diabetes Medicine Neuroscience S&P 500 Alzheimer's Disease Anemia Asthma Cholesterol Depressive Disorder Hormones Hypertension Life Sciences Major Depressive Disorder Medication