HELX vs. SBIO ETF Comparison

Comparison of Franklin Genomic Advancements ETF (HELX) to ALPS Medical Breakthroughs ETF (SBIO)
HELX

Franklin Genomic Advancements ETF

HELX Description

Seeks capital appreciation by investing in innovative companies related to genomic-based technologies designed to enhance the quality of life. Provides access to companies benefitting from or facilitating the use of new research including DNA sequencing, gene editing and personalized medicine Uses bottom-up fundamental research conducted by dedicated, industry-specific analysts to identify disruptive business models at the right stage for investment Actively managed by a seasoned portfolio management team that is based in Silicon Valley and has a long history of investing in the craft of innovation

Grade (RS Rating)

Last Trade

$29.52

Average Daily Volume

2,553

Number of Holdings *

53

* may have additional holdings in another (foreign) market
SBIO

ALPS Medical Breakthroughs ETF

SBIO Description The investment seeks investment results that correspond (before fees and expenses) generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs IndexSM. The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small- and mid-cap stocks of biotechnology and pharmaceutical companies that have one or more drugs in either Phase II or Phase III U.S. Food and Drug Administration clinical trials. It is non-diversified.

Grade (RS Rating)

Last Trade

$37.19

Average Daily Volume

8,401

Number of Holdings *

83

* may have additional holdings in another (foreign) market
Performance
Period HELX SBIO
30 Days -8.43% -5.42%
60 Days -11.31% -4.19%
90 Days -11.94% 2.30%
12 Months 6.08% 47.72%
4 Overlapping Holdings
Symbol Grade Weight in HELX Weight in SBIO Overlap
CRNX B 0.25% 2.95% 0.25%
FDMT F 0.1% 0.31% 0.1%
KRYS C 4.7% 3.39% 3.39%
NTLA F 0.51% 0.94% 0.51%
HELX Overweight 49 Positions Relative to SBIO
Symbol Grade Weight
VRTX D 5.94%
NTRA A 4.64%
LLY F 4.63%
REGN F 4.3%
MEDP F 4.07%
TMO D 4.01%
DHR D 3.99%
UTHR C 2.75%
AZN F 2.34%
CDNS B 2.34%
CTVA C 2.29%
CRL D 2.23%
BNTX D 2.21%
A F 2.11%
IONS F 2.1%
INSM C 2.08%
RVTY D 2.01%
ALNY D 1.98%
QGEN D 1.96%
BRKR F 1.94%
SRPT F 1.5%
RARE F 1.46%
RCKT F 1.42%
TWST F 1.27%
LGND C 1.27%
ICLR D 1.25%
EXAS D 1.2%
LH B 1.15%
IQV F 1.08%
RGEN D 1.08%
BEAM D 1.03%
TECH F 1.01%
VYGR F 0.99%
AZTA D 0.95%
NBIX C 0.94%
BBIO F 0.91%
RXRX D 0.69%
MRNA F 0.66%
BIO C 0.59%
VCYT B 0.56%
DVAX C 0.53%
DOCS C 0.51%
CDMO A 0.51%
CRSP D 0.5%
AVTR F 0.46%
BMY B 0.36%
BMRN F 0.2%
ARE F 0.15%
SLP F 0.11%
HELX Underweight 79 Positions Relative to SBIO
Symbol Grade Weight
CORT B -3.66%
RNA C -3.29%
ACLX C -3.19%
ALKS C -3.15%
IMVT F -2.66%
DNLI D -2.36%
MRUS F -2.21%
AGIO C -2.05%
PTCT B -2.02%
XENE D -2.01%
VRNA A -1.98%
FOLD F -1.95%
EWTX C -1.92%
ACAD C -1.89%
VERA C -1.82%
ZLAB C -1.79%
VCEL A -1.73%
PTGX D -1.61%
CGON F -1.57%
IDYA F -1.53%
GERN C -1.48%
MIRM B -1.47%
KROS D -1.4%
LBPH A -1.4%
AKRO C -1.32%
MNKD B -1.26%
IRON B -1.21%
GLPG F -1.19%
TARS C -1.16%
IMCR C -1.07%
CLDX D -1.06%
ARVN F -1.06%
BCRX D -0.99%
XNCR B -0.98%
RCUS F -0.95%
SNDX F -0.93%
SPRY C -0.88%
VRDN D -0.84%
KURA F -0.83%
DAWN D -0.82%
AUPH C -0.78%
PHVS D -0.76%
APLT B -0.72%
COGT D -0.69%
ETNB D -0.57%
LQDA F -0.54%
PLRX D -0.53%
PRTA F -0.52%
ERAS C -0.51%
REPL C -0.5%
IRWD F -0.44%
AVXL B -0.42%
ANNX F -0.4%
MLYS F -0.39%
ALT C -0.37%
OLMA F -0.37%
ANAB F -0.36%
FLGT F -0.35%
ALLO F -0.35%
CELC F -0.34%
YMAB F -0.34%
URGN F -0.34%
SVRA F -0.34%
FULC F -0.33%
TBPH B -0.32%
GHRS B -0.31%
ARCT F -0.31%
AURA C -0.3%
ALEC F -0.28%
CMPS F -0.23%
ACIU D -0.22%
VNDA C -0.2%
ITOS F -0.19%
STRO F -0.17%
ALDX D -0.17%
ZNTL D -0.17%
ENTA F -0.14%
INZY F -0.12%
HLVX F -0.06%
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