HELX vs. CANC ETF Comparison

Comparison of Franklin Genomic Advancements ETF (HELX) to Tema Oncology ETF (CANC)
HELX

Franklin Genomic Advancements ETF

HELX Description

Seeks capital appreciation by investing in innovative companies related to genomic-based technologies designed to enhance the quality of life. Provides access to companies benefitting from or facilitating the use of new research including DNA sequencing, gene editing and personalized medicine Uses bottom-up fundamental research conducted by dedicated, industry-specific analysts to identify disruptive business models at the right stage for investment Actively managed by a seasoned portfolio management team that is based in Silicon Valley and has a long history of investing in the craft of innovation

Grade (RS Rating)

Last Trade

$30.51

Average Daily Volume

1,729

Number of Holdings *

51

* may have additional holdings in another (foreign) market
CANC

Tema Oncology ETF

CANC Description Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from oncology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$27.91

Average Daily Volume

3,114

Number of Holdings *

43

* may have additional holdings in another (foreign) market
Performance
Period HELX CANC
30 Days -4.73% -0.85%
60 Days -8.33% -6.56%
90 Days -6.94% -1.34%
12 Months 16.57% 24.12%
6 Overlapping Holdings
Symbol Grade Weight in HELX Weight in CANC Overlap
BNTX B 1.85% 0.93% 0.93%
CRSP C 0.65% 2.22% 0.65%
EXAS A 1.73% 2.27% 1.73%
MRNA F 0.79% 0.94% 0.79%
NTLA F 0.83% 2.05% 0.83%
REGN F 5.0% 5.42% 5.0%
HELX Overweight 45 Positions Relative to CANC
Symbol Grade Weight
MEDP F 5.91%
VRTX D 5.79%
DHR D 5.27%
LLY F 4.97%
TMO D 4.96%
KRYS C 4.25%
NTRA B 3.8%
AZN F 2.68%
CTVA A 2.27%
INSM D 2.11%
A D 2.08%
IONS F 2.05%
BRKR D 2.01%
ALNY C 1.99%
CDNS C 1.98%
CRL F 1.95%
UTHR A 1.86%
QGEN D 1.85%
ICLR F 1.66%
RCKT F 1.57%
SRPT D 1.56%
RVTY C 1.48%
RARE D 1.46%
TWST F 1.22%
IQV F 1.13%
VYGR C 1.11%
LH A 0.97%
BBIO D 0.92%
TECH B 0.91%
LGND A 0.88%
AZTA F 0.86%
BEAM F 0.86%
NBIX C 0.84%
CDMO C 0.8%
RXRX F 0.57%
RGEN D 0.54%
BIO A 0.53%
AVTR F 0.5%
FDMT F 0.44%
BMY A 0.31%
SLP F 0.3%
VCYT A 0.24%
DVAX A 0.2%
BMRN F 0.2%
ARE F 0.16%
HELX Underweight 37 Positions Relative to CANC
Symbol Grade Weight
AMGN C -5.42%
GILD A -4.36%
ARGX A -3.87%
RVMD A -3.83%
ILMN A -3.83%
INCY A -3.38%
BPMC C -3.14%
MRK F -2.8%
MREO D -2.78%
BGNE C -2.58%
EXEL A -2.33%
NVS D -2.18%
AGIO B -2.13%
NUVL D -2.03%
GMAB F -1.94%
DAWN A -1.87%
LEGN F -1.81%
ACLX B -1.69%
LNTH C -1.65%
CLDX F -1.58%
MRUS C -1.42%
JANX A -1.42%
GH D -1.38%
SWTX D -1.21%
COGT B -1.19%
SDGR F -1.06%
BCYC D -0.93%
IDYA F -0.89%
CGEM F -0.83%
NRIX B -0.8%
RLAY F -0.76%
ORIC D -0.75%
RCUS F -0.72%
IMCR F -0.67%
TERN D -0.63%
CGON F -0.55%
ARVN C -0.48%
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