CANC vs. HDEF ETF Comparison

Comparison of Tema Oncology ETF (CANC) to Deutsche X-trackers MSCI EAFE High Dividend Yield Hedged Equity ETF (HDEF)

CANC

Tema Oncology ETF

CANC Description

Under normal circumstances, the fund seeks to achieve its investment objective by investing at least 80% of its net assets, which include borrowings for investment purposes, in publicly listed companies that derive at least 50% of revenues from oncology. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$26.62

Average Daily Volume

2,712

Number of Holdings ^*

43

* may have additional holdings in another (foreign) market

HDEF

Deutsche X-trackers MSCI EAFE High Dividend Yield Hedged Equity ETF

HDEF Description

The investment seeks investment results that correspond generally to the performance, before fees and expenses, of the MSCI EAFE High Dividend Yield US Dollar Hedged Index. The fund will invest at least 80% of its total assets (but typically far more) in component securities of the underlying index. The underlying index is designed to reflect the performance of equities in its parent index, the MSCI EAFE Index, with higher dividend income and quality characteristics than average dividend yields of equities in the parent index, where such higher dividend income and quality characteristics are both sustainable and persistent. The fund is non-diversified.

Grade (RS Rating)

Last Trade

$24.82

Average Daily Volume

206,766

Number of Holdings ^*

4

* may have additional holdings in another (foreign) market

Performance

Period	CANC	HDEF
30 Days	-6.65%	-4.50%
60 Days	-10.02%	-6.30%
90 Days	-10.36%	-3.79%
12 Months	15.15%	11.08%

1 Overlapping Holdings

	Symbol	Grade	Weight in CANC	Weight in HDEF	Overlap
	NVS	D	2.03%	5.14%	2.03%

CANC Overweight 42 Positions Relative to HDEF

	Symbol	Grade	Weight
	GILD	B	5.49%
	REGN	F	5.25%
	RVMD	B	4.6%
	ARGX	A	4.19%
	ILMN	C	4.16%
	INCY	C	4.1%
	BPMC	C	4.05%
	EXEL	B	2.93%
	MRK	F	2.81%
	AGIO	C	2.71%
	MREO	F	2.54%
	AMGN	D	2.37%
	BGNE	D	2.3%
	CRSP	D	2.3%
	SWTX	C	2.14%
	GH	B	2.07%
	NUVL	D	1.99%
	DAWN	D	1.9%
	GMAB	F	1.84%
	NTLA	F	1.58%
	ACLX	C	1.5%
	EXAS	D	1.45%
	CLDX	D	1.44%
	SDGR	C	1.44%
	JANX	C	1.43%
	LEGN	D	1.41%
	MRUS	F	1.37%
	LNTH	C	1.22%
	NRIX	C	1.15%
	COGT	D	0.95%
	IDYA	F	0.9%
	BNTX	D	0.89%
	BCYC	F	0.84%
	CGEM	F	0.83%
	ORIC	F	0.76%
	MRNA	F	0.72%
	RLAY	F	0.69%
	IMCR	C	0.69%
	RCUS	F	0.67%
	TERN	F	0.6%
	CGON	F	0.56%
	ARVN	F	0.46%

CANC Underweight 3 Positions Relative to HDEF

	Symbol	Grade	Weight
	UL	D	-5.05%
	STLA	F	-1.0%
	AGCO	F	-0.21%

CANC: Top Represented Industries & Keywords

Industries: Biotechnology Diagnostics & Research Drug Manufacturers - Major Health Information Services Long-Term Care Facilities

Keywords: Cancer Biopharmaceutical Medicine Biotechnology Clinical Medicine Solid Tumors Immunology Disease Life Sciences Monoclonal Antibodies Nasdaq 100 Precision Medicine S&P 500 Acute Myeloid Leukemia Biology Drug Discovery Enzymes Genetics Immune System Immunotherapies

HDEF: Top Represented Industries & Keywords

Industries: Auto Manufacturers Drug Manufacturers - Major Farm & Construction Equipment Household & Personal Products

Keywords: Active Pharmaceutical Ingredients Agricultural Equipment Agricultural Machinery Agriculture Alternative Fuel Animal Health Antibiotics Automotive Manufacturers Baler Beef Biotechnology Blood Test Cars Cattle Chrysler Cleaning Products Contact Lens Contact Lenses Crop Protection Chemicals Crops