BBC vs. FPXE ETF Comparison

Comparison of Virtus LifeSci Biotech Clinical Trials ETF (BBC) to First Trust IPOX Europe Equity Opportunities ETF (FPXE)

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BBC Description

The Fund seeks investment results that correspond, before fees and expenses, to the price and yield performance of the LifeSci Biotechnology Clinical Trials Index, which tracks the performance of select clinical trials stage biotechnology companies.

Grade (RS Rating)

Last Trade

$27.58

Average Daily Volume

1,864

Number of Holdings ^*

101

* may have additional holdings in another (foreign) market

FPXE

First Trust IPOX Europe Equity Opportunities ETF

FPXE Description

The First Trust IPOX® Europe Equity Opportunities ETF (the "Fund") seeks investment results that correspond generally to the price and yield (before the Fund's fees and expenses) of an equity index called the IPOX® 100 Europe Index (the "Index"). The Fund will normally invest at least 90% of its net assets (including investment borrowings) in common stocks and/or depositary receipts that comprise the Index. The Fund, using an indexing investment approach, attempts to replicate, before fees and expenses, the performance of the Index. The Fund's investment advisor seeks a correlation of 0.95 or better (before fees and expenses) between the Fund's performance and the performance of the Index; a figure of 1.00 would represent perfect correlation. The Index is owned, developed, maintained and sponsored by IPOX® Schuster LLC (the "Index Provider").

Grade (RS Rating)

Last Trade

$26.25

Average Daily Volume

1,169

Number of Holdings ^*

* may have additional holdings in another (foreign) market

Performance

Period	BBC	FPXE
30 Days	-1.58%	-1.36%
60 Days	1.78%	7.93%
90 Days	12.19%	2.14%
12 Months	45.59%	33.40%

3 Overlapping Holdings

Symbol	Grade	Weight in BBC	Weight in FPXE	Overlap
CNTA	B	1.32%	0.58%	0.58%
IMTX	F	0.75%	0.39%	0.39%
MRUS	D	0.68%	0.7%	0.68%

BBC Overweight 98 Positions Relative to FPXE

Symbol	Grade	Weight
SMMT	D	2.14%
IGMS	C	1.77%
VRDN	A	1.47%
LBPH	D	1.33%
APLT	B	1.3%
PCVX	B	1.26%
ACLX	C	1.23%
EWTX	B	1.21%
SAVA	D	1.19%
ORIC	D	1.15%
KYMR	D	1.15%
NRIX	D	1.14%
DNLI	C	1.1%
ANAB	D	1.09%
PTGX	C	1.07%
IRON	C	1.06%
WVE	B	1.06%
NUVL	B	1.04%
ERAS	D	1.02%
COGT	C	1.01%
ABUS	D	1.0%
REPL	B	0.98%
VKTX	C	0.98%
TYRA	C	0.97%
VERA	C	0.96%
ALLO	F	0.95%
AKRO	C	0.95%
KROS	B	0.94%
RVMD	B	0.92%
ELVN	B	0.91%
CGON	C	0.9%
JANX	D	0.9%
TERN	D	0.89%
CRNX	C	0.89%
RNA	B	0.88%
IMVT	F	0.87%
SVRA	F	0.86%
ANNX	B	0.85%
PHVS	D	0.85%
XENE	D	0.84%
ALEC	F	0.83%
ARQT	D	0.83%
DYN	D	0.83%
CYTK	F	0.82%
BEAM	F	0.82%
OLMA	F	0.81%
CMPS	F	0.81%
QURE	F	0.8%
XNCR	D	0.79%
RLAY	F	0.79%
BCYC	D	0.79%
MLYS	B	0.78%
CELC	F	0.78%
PRTA	F	0.78%
PLRX	F	0.78%
SLN	D	0.77%
SRRK	F	0.77%
BLTE	C	0.77%
ARVN	F	0.77%
SNDX	F	0.76%
KURA	F	0.75%
RCUS	F	0.75%
CLDX	F	0.75%
VERV	F	0.74%
IMNM	F	0.74%
RGNX	F	0.68%
RCKT	F	0.67%
NTLA	F	0.67%
IDYA	F	0.66%
NUVB	F	0.66%
AUTL	F	0.66%
ETNB	F	0.65%
ABCL	F	0.65%
CGEM	F	0.65%
LQDA	F	0.62%
CVAC	F	0.62%
RXRX	F	0.61%
ARWR	F	0.61%
VIR	F	0.6%
ARCT	D	0.58%
STOK	D	0.58%
LRMR	F	0.56%
MGNX	F	0.56%
ITOS	F	0.53%
EDIT	F	0.52%
SANA	F	0.5%
LYEL	F	0.48%
PGEN	F	0.46%
TSHA	F	0.41%
FULC	F	0.4%
FDMT	F	0.37%
PRME	F	0.36%
ZNTL	F	0.33%
CABA	F	0.28%
ALXO	F	0.19%
SCLX	F	0.14%
HLVX	F	0.1%
AVTE	D	0.07%

BBC Underweight 15 Positions Relative to FPXE

Symbol	Grade	Weight
ARM	C	-6.8%
SPOT	B	-4.17%
MNDY	C	-4.15%
ONON	C	-3.59%
CLBT	C	-1.56%
HAFN	B	-1.47%
TEVA	D	-0.87%
JHG	C	-0.53%
SPNT	D	-0.43%
BIRK	F	-0.41%
VRNA	C	-0.19%
GENI	D	-0.17%
SRAD	C	-0.16%
OSW	C	-0.08%
DOLE	C	-0.07%